Results 61 to 70 of about 40,088 (308)
CXCR2 deficient mice display macrophage-dependent exaggerated acute inflammatory responses [PDF]
, 2017 CXCR2 is an essential regulator of neutrophil recruitment to inflamed and damaged sites and plays prominent roles in inflammatory pathologies and cancer. It has therefore been highlighted as an important therapeutic target.
A Mantovani +38 more
core +1 more source
Effect of Zymosan on Endotoxin Toxicity in Mice.
Experimental Biology and Medicine, 1959 SummaryZymosan renders mice highly susceptible to the lethal effect of endotoxin at a time when activity of the R.E.S. is greatly stimulated. This effect is similar to that following B.C.G. infection. Pretreatment with cortisone abolishes nearly completely the increased toxicity to endotoxin caused by zymosan or B.C.G. infection.
D. Jacoby +2 more
openaire +3 more sources
Research and Reports in Urology, 2023 Ashley C Archer,1 Jennifer J DeBerry,2 Cary DeWitte,2 Timothy J Ness2 1University of Alabama at Birmingham School of Medicine, Birmingham, AL, USA; 2Department of Anesthesiology and Perioperative Medicine, University of Alabama at Birmingham, Birmingham,
Archer AC +3 more
doaj
HMGB1 Inhibition During Zymosan-Induced Inflammation: The Potential Therapeutic Action of Riboflavin
Archivum Immunologiae et Therapiae Experimentalis, 2015 Sepsis, also known as systemic inflammatory response syndrome, is a life-threatening condition caused by a pathogenic agent and leading to multiple organ dysfunction syndrome.
A. Mazur-Biały, E. Pocheć
semanticscholar +1 more source
Anti-atherogenic properties associated with the antioxidant activity from the hydrophilic extracts of Halimeda incrassata (Chlorophyta, Bryopsidales) [PDF]
, 2017 Seaweeds are a source of natural antioxidants having potential application in oxidative stress and associated diseases. In this work, anti-atherogenic properties associated with the antioxidant activity from the hydrophilic extracts of Halimeda ...
Claudina, Zaldívar-Munoz +8 more
core +1 more source
Riboflavin: The Health Benefits of a Forgotten Natural Vitamin [PDF]
, 2020 Riboflavin (RF) is a water-soluble member of the B-vitamin family. Sufficient dietary and supplemental RF intake appears to have a protective effect on various medical conditions such as sepsis, ischemia etc., while it also contributes to the reduction ...
Bäumler, Hans +4 more
core +1 more source
Blood, 2011 Human mesenchymal stem/progenitor cells (hMSCs) repair tissues and modulate immune systems but the mechanisms are not fully understood. We demonstrated that hMSCs are activated by inflammatory signals to secrete the anti-inflammatory protein, TNF-α ...
Hosoon Choi +4 more
semanticscholar +1 more source
Discovery of orexant and anorexant agents with indazole scaffold endowed with peripheral antiedema activity [PDF]
, 2019 CB1 receptors and endocannabinoids are integrated components of neuronal networks controlling different organism’s functions, such as appetite and food intake in the hypothalamus.
Dimmito, Marilisa P. +7 more
core +2 more sources
Paradoxical Activation of Entheseal Myeloid Cells by JAK1 and TYK2 Inhibitors via IL10 Antagonism
Arthritis &Rheumatology, Accepted Article.Background JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but TYK2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn's Disease, which highlights the complex role for JAK‐STAT signaling in different inflammatory processes. In this study, we investigated
Sami Giryes +14 more
wiley +1 more source
Acta Cirurgica Brasileira, 2014 PURPOSE To evaluate the effect of curcumin in the acute phase of zymosan-induced arthritis. METHODS Twenty-eight male rats were subjected to intra-articular infiltration of zymosan of both knees and, in four the infiltration was made with saline.
Nilson Nonose +5 more
semanticscholar +1 more source