Results 71 to 80 of about 40,088 (308)

C13orf31 (FAMIN) is a central regulator of immunometabolic function. [PDF]

, 2016
Single-nucleotide variations in C13orf31 (LACC1) that encode p.C284R and p.I254V in a protein of unknown function (called 'FAMIN' here) are associated with increased risk for systemic juvenile idiopathic arthritis, leprosy and Crohn's disease.

core   +2 more sources

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

Chemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves, Giulia Cristina de Andreoli Souza, Alvaro Jose Hernandez Tasco, Marcos José Salvador   +3 more
wiley   +1 more source

Effects of pH on the Adsorption and Desorption of Naringin onto Zymosan A in Aqueous Systems [PDF]

Chemical and Biochemical Engineering Quarterly
This study aimed to investigate the interactions between naringin and dietary fiber from yeast (zymosan A) through adsorption and desorption processes. The effects of different solution pH conditions (pH 3.0, pH 7.0, and pure water at pH 5.5), as well as
P. Matić, P. Pőc, L. Šoher, D. Kenjerić, L. Jakobek   +4 more
doaj   +1 more source

Plunder of Human Blood Leukocytes Containing Ingested Material, by Other Leukocytes: Where Is the Fusagen That Allows Preservation of Membrane Integrity and Motile Function? [PDF]

PLoS ONE, 2013
In studying phagocytosis of zymosan particles by human blood monocytes in phase-contrast videomicroscopy, we found that monocytes loaded with zymosan particles became chemotactic for polymorphonuclear leukocytes (PMN) which closed on them and purloined ...
Stephen E Malawista, Anne Chevance de Boisfleury   +1 more
doaj   +1 more source

First‐in‐Human Single and Multiple Ascending Dose Studies of Balinatunfib, a Small Molecule Inhibitor of TNFR1 Signaling in Healthy Participants

Clinical Pharmacology &Therapeutics, EarlyView.
Oral small molecule inhibitors of tumor necrosis factor alpha (TNFα) are emerging as attractive therapeutic agents for the treatment of various autoimmune diseases. Balinatunfib (SAR441566), a novel oral inhibitor of tumor necrosis factor receptor 1 (TNFR1) signaling, changes the configuration of the soluble TNFα (sTNFα) trimer and prevents its ...
Nassr Nassr, Faiza Rharbaoui, Dietmar Weitz, Johann Gassenhuber, Markus Rehberg, Markus Kohlmann, Fabienne Schumacher, Amel Lahmar, Andreas Kovar, Laurent Perrin, Frank‐Dietrich Wagner, Maria Wiekowski, Mai Anh Nguyen   +12 more
wiley   +1 more source

Hematopoietic Stem/Progenitor Cell Dependent Participation of Innate Lymphoid Cells in Low-Intensity Sterile Inflammation

Frontiers in Immunology, 2018
Hematopoietic stem/progenitor cells (HSPC) are characterized by their unique capacities of self-renewal and multi-differentiation potential. This second property makes them able to adapt their differentiation profile depending on the local environment ...
Sarantis Korniotis, Thomas B. Thornley, Periklis Kyriazis, Evangelos Theodorou, Evangelos Theodorou, Lingzhi Ma, Lisa S. Li, Efi Kokkotou, Efi Kokkotou, Terry B. Strom, Terry B. Strom, Maria Koulmanda, Maria Koulmanda   +12 more
doaj   +1 more source

Breast Cancer Associated Metastasis is Significantly Increased in a Model of Autoimmune Arthritis [PDF]

, 2008
Chronic inflammation is known to play a role in cancer initiation, promotion,and metastasis. However, the mechanism by which inflammation promotes metastasis is still unclear.
Latha Pathangey, Lopamudra Das Roy, Pinku Mukherjee, Teresa Tinder   +3 more
core   +1 more source

Noninflammatory Changes of Microglia Are Sufficient to Cause Epilepsy. [PDF]

, 2018
Microglia are well known to play a critical role in maintaining brain homeostasis. However, their role in epileptogenesis has yet to be determined.
Adamo, Matthew A, Chang, Julia, Feustel, Paul, Gruenthal, Michael, Huang, Yunfei, Liao, Yuan, Mathern, Gary W, Mathur, Ramkumar, Mazurkiewicz, Joseph, Morgan, Shannon, Qian, Jiang, Ritaccio, Anthony L, Zhao, Xiaofeng, Zhu, Xinjun   +13 more
core   +2 more sources

Agmatine Protects against Zymosan-Induced Acute Lung Injury in Mice by Inhibiting NF-κB-Mediated Inflammatory Response

BioMed Research International, 2014
Acute lung injury (ALI) is characterized by overwhelming lung inflammation and anti-inflammation treatment is proposed to be a therapeutic strategy for ALI.
Xuanfei Li, Zheng Liu, He Jin, Xia Fan, Xue Yang, Wanqi Tang, Jun Yan, Huaping Liang   +7 more
semanticscholar   +1 more source

Neutrophil Function in Patients With Chronic Kidney Disease: A Systematic Review and Meta‐Analysis

Acta Physiologica, Volume 241, Issue 6, June 2025.
ABSTRACT Background Patients with chronic kidney disease (CKD) are at increased cardiovascular risk. Since neutrophils play a central role in atherosclerosis and cardiovascular disease, this study analyzed neutrophil function in CKD patients. Methods A systematic review of neutrophil function in CKD patients compared to controls was performed according
Jane Sophie Lauxen, Sonja Vondenhoff, Carolina Victoria Cruz Junho, Philipp Martin, Susanne Fleig, Katharina Schütt, Ulrike Schulze‐Späte, Oliver Soehnlein, Leticia Prates‐Roma, Yvonne Döring, Constance C. F. M. J. Baaten, Heidi Noels   +11 more
wiley   +1 more source