Results 11 to 20 of about 105,937 (401)
Prophylactic Anticonvulsants in Intracerebral Hemorrhage [PDF]
Neurocritical Care, 2017 Background and Purpose Prophylactic anticonvulsants are routinely prescribed in the acute setting for intracerebral hemorrhage (ICH) patients, but some studies have reported an association with worse outcomes.
J. Mackey +10 more
semanticscholar +3 more sources
Familial Bainbridge‐Ropers syndrome: Report of familial ASXL3 inheritance and a milder phenotype
American Journal of Medical Genetics Part A, Volume 191, Issue 1, Page 29-36, January 2023., 2023 Abstract De novo truncating and splicing pathogenic variants in the Additional Sex Combs‐Like 3 (ASXL3) gene are known to cause neurodevelopmental delay, intellectual disability, behavioral difficulties, hypotonia, feeding problems and characteristic facial features.
Schaida Schirwani +10 more
wiley +1 more source
Genetic and phenotypic spectrum in the NONO‐associated syndromic disorder
American Journal of Medical Genetics Part A, Volume 191, Issue 2, Page 469-478, February 2023., 2023 Abstract The non‐POU domain‐containing octamer‐binding (NONO) protein is involved in multiple steps of gene regulation such as RNA metabolism and DNA repair. Hemizygous pathogenic variants in the NONO gene were confirmed to cause a rare X‐linked syndromic disorder. Through our in‐house diagnostics and subsequent matchmaking, we identified six unrelated
Franziska Roessler +21 more
wiley +1 more source
Anticonvulsants in neuropathic pain: rationale and clinical evidence
European Journal of Pain, 2002 Troels Staehelin Jensen, Dirk J Duncker
exaly +2 more sources
Comparative vascular effects of levetiracetam and valproate with hyperhomocysteinemia in rat models
Türk Biyokimya Dergisi, 2023 Hyperhomocysteinemia (HHcy) a significant risk factor for vascular disease, often emerges in epilepsy with the use of antiepileptic drugs. In this relationship, our study investigates the combined effects of HHcy and antiepileptics on vascular function ...
Gökdemir Selim +6 more
doaj +1 more source
Role of Anticonvulsants in the Management of AIDS related Seizures
Frontiers in Neurology, 2014 Seventy percent of the AIDS patients have neurological complications. Seizures are one of the complications and can occur at any stage. Seizures can be life–threatening and treatment with anticonvulsants is warranted.
BATOOL F. KIRMANI +1 more
doaj +1 more source
Canadian Medical Association Journal, 2018 BACKGROUND: The use of anticonvulsants (e.g., gabapentin, pregabalin) to treat low back pain has increased substantially in recent years despite limited supporting evidence.
Oliver Enke +7 more
semanticscholar +1 more source
Early Administration of Gabapentinoids Improves Motor Recovery after Human Spinal Cord Injury
Cell Reports, 2017 The anticonvulsant pregabalin promotes neural regeneration in a mouse model of spinal cord injury (SCI). We have also previously observed that anticonvulsants improve motor outcomes following human SCI.
Freda M. Warner +10 more
doaj +1 more source
Cognitive Effects of Anticonvulsants
Pediatric Neurology Briefs, 1990 The neuropsychological effects of carbamazepine, phenobarbital, and phenytoin in 15 patients with partial complex epilepsy were investigated at the Department of Neurology, Medical College of Georgia, Augusta, GA.
J Gordon Millichap
doaj +1 more source
Mechanism of sodium channel block by local anesthetics, antiarrhythmics, and anticonvulsants
The Journal of General Physiology, 2017 Local anesthetics, antiarrhythmics, and anticonvulsants include both charged and electroneutral compounds that block voltage-gated sodium channels. Prior studies have revealed a common drug-binding region within the pore, but details about the binding ...
D. Tikhonov, B. Zhorov
semanticscholar +1 more source