Results 11 to 20 of about 437,849 (236)

New Approaches for Cryptococcosis Treatment

open access: yesMicroorganisms, 2020
Cryptococcosis is an important opportunistic infection and a leading cause of meningitis in patients with HIV infection. The antifungal pharmacological treatment is limited to amphotericin B, fluconazole and 5- flucytosine.
Cristina de Castro Spadari   +3 more
doaj   +1 more source

Nanocarriers Provide Sustained Antifungal Activity for Amphotericin B and Miltefosine in the Topical Treatment of Murine Vaginal Candidiasis

open access: yesFrontiers in Microbiology, 2020
Topical drug administration is frequently used for the treatment of vaginal candidiasis; however, most formulations using this route do not provide prolonged drug release.
Fernanda Walt Mendes da Silva de Bastiani   +5 more
doaj   +1 more source

Utilization Trends of Antiviral and Antifungal Agents for Human Systemic Use in Tanzania From 2010 to 2017 Using the World Health Organization Collaborating Centre for Drug Statistics Methodology

open access: yesFrontiers in Tropical Diseases, 2021
Introduction The increase in antimicrobial consumption contributes to the emergence of antimicrobial resistance (AMR). Many studies have investigated the patterns of antibacterial consumption and antibacterial resistance.
Hafidh Hamim   +8 more
semanticscholar   +1 more source

Symbiont-Mediated Protection of Acromyrmex Leaf-Cutter Ants from the Entomopathogenic Fungus Metarhizium anisopliae

open access: yesmBio, 2021
Many fungus-growing ants engage in a defensive symbiosis with antibiotic-producing ectosymbiotic bacteria in the genus Pseudonocardia, which help protect the ants’ fungal mutualist from a specialized mycoparasite, Escovopsis.
Gaspar Bruner-Montero   +5 more
doaj   +1 more source

Antifungal Drug Resistance: Molecular Mechanisms in Candida albicans and Beyond.

open access: yesChemical Reviews, 2020
Fungal infections are a major contributor to infectious disease-related deaths across the globe. Candida species are among the most common causes of invasive mycotic disease, with Candida albicans reigning as the leading cause of invasive candidiasis ...
Yunjin Lee   +3 more
semanticscholar   +1 more source

The Essential Thioredoxin Reductase of the Human Pathogenic Mold Aspergillus fumigatus Is a Promising Antifungal Target

open access: yesFrontiers in Microbiology, 2020
The identification of cellular targets for antifungal compounds is a cornerstone for the development of novel antimycotics, for which a significant need exists due to increasing numbers of susceptible patients, emerging pathogens, and evolving resistance.
Jasmin Binder   +5 more
doaj   +1 more source

Candida auris: Epidemiology, biology, antifungal resistance, and virulence

open access: yesPLoS Pathogens, 2020
First described in 2009 in Japan, the emerging multidrug-resistant fungal pathogen Candida auris is becoming a worldwide public health threat that has been attracting considerable attention due to its rapid and widespread emergence over the past decade ...
Han Du   +5 more
semanticscholar   +1 more source

Candidiasis and Mechanisms of Antifungal Resistance

open access: yesAntibiotics, 2020
Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which is caused by more than 20 types of Candida sp., with C. albicans being the most common.
Somanon Bhattacharya   +2 more
semanticscholar   +1 more source

Three New Isoflavonoid Glycosides from the Mangrove-Derived Actinomycete Micromonospora aurantiaca 110B

open access: yesMarine Drugs, 2019
The mangrove ecosystem is a rich resource for the discovery of actinomycetes with potential applications in pharmaceutical science. Besides the genus Streptomyces, Micromonospora is also a source of new bioactive agents.
Rui-Jun Wang   +8 more
doaj   +1 more source

Probiotic Characteristics and Antifungal Activity of Lactobacillus plantarum and Its Impact on Fermentation of Italian Ryegrass at Low Moisture

open access: yesApplied Sciences, 2020
The study aimed to investigate probiotic characteristics, and low moisture silage fermentation capability of selected lactic acid bacteria (LAB) isolated from Alfalfa (Medicago sativa L).
Karnan Muthusamy   +6 more
doaj   +1 more source

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