Results 11 to 20 of about 56,494 (234)
Dictyostelium discoideum as a non‐mammalian biomedical model
Microbial Biotechnology, 2021 Summary Dictyostelium discoideum is one of eight non‐mammalian model organisms recognized by the National Institute of Health for the study of human pathology. The use of this slime mould is possible owing to similarities in cell structure, behaviour and
Javier Martín‐González +2 more
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Multiscale modeling of oscillations and spiral waves in Dictyostelium populations [PDF]
Physical review. E, Statistical, nonlinear, and soft matter physics, 2014 Unicellular organisms exhibit elaborate collective behaviors in response to environmental cues. These behaviors are controlled by complex biochemical networks within individual cells and coordinated through cell-to-cell communication.
Gregor, Thomas +4 more
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BioTechniques, 2013 The loading controls used for quantitative immunoblotting of mammalian proteins are not appropriate for use with Dictyostelium discoideum. Actin levels, for example, change greatly during Dictyostelium development.
Andrew J. Davidson +2 more
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PLoS ONE, 2014 The neuronal ceroid lipofuscinoses (NCL) are a group of inherited, severe neurodegenerative disorders also known as Batten disease. Juvenile NCL (JNCL) is caused by recessive loss-of-function mutations in CLN3, which encodes a transmembrane protein that ...
Robert J Huber +2 more
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Frontiers in Cellular and Infection Microbiology, 2013 Dictyostelium cells are forest soil amoebae, which feed on bacteria and proliferate as solitary cells until bacteria are consumed. Starvation triggers a change in life style, forcing cells to gather into aggregates to form multicellular organisms ...
Salvatore eBozzaro +2 more
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Identification and phylogenetic analysis of
BMC Genomics, 2003 Background Kinesins constitute a large superfamily of motor proteins in eukaryotic cells. They perform diverse tasks such as vesicle and organelle transport and chromosomal segregation in a microtubule- and ATP-dependent manner.
Glöckner Gernot, Kollmar Martin
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The Dictyostelium Centrosome [PDF]
Cells, 2021 The centrosome of Dictyostelium amoebae contains no centrioles and consists of a cylindrical layered core structure surrounded by a corona harboring microtubule-nucleating γ-tubulin complexes. It is the major centrosomal model beyond animals and yeasts.
Ralph Gräf +4 more
openaire +3 more sources
Production of antibacterial compounds by a Steely hybrid polyketide synthase in Dictyostelium. [PDF]
FEBS Open BioBy selecting appropriate production species under optimised culture conditions, new chlorinated dibenzofuran compounds, which previously could not be analysed in sufficient quantities, were identified from cellular slime mould fruiting bodies. The strong antibacterial activity exhibited by these compounds suggests a link to the ecological function of ...
Yamashita TR, Usuki T, Kay RR, Saito T.
europepmc +2 more sources
Gel purification of gDNA for next-generation sequencing applications
BioTechniques, 2022 We demonstrate that gDNA can be conveniently and efficiently isolated and purified using standard agarose gel electrophoresis, band excision and gel purification.
Supanut Utthiya +6 more
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The proppin Bcas3 and its interactor KinkyA localize to the early phagophore and regulate autophagy [PDF]
, 2021 To resolve the signaling mechanisms that mediate the starvation-induced processes of Dictyostelium sporulation and encystation, we performed insertional mutagenesis on cells harboring an mRFP-tagged spore gene.
Schaap, Pauline, Yamada, Yoko
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