Pattern formation in Dictyostelium [PDF]
INTRODUCTION Upon starvation, amoebae of the cellular slime mold Dictyostelium undergo a program of development in which individual cells aggregate to form a multicellular slug and, subsequently, a fruiting body consisting of stalk cells and spores (Loomis 1982).
David, Charles N.+2 more
core +4 more sources
Effect of Retinal on Dictyostelium Cells During Development. [PDF]
When all‐trans‐retinal was added to the medium, Dictyostelium cells retracted their pseudopodia and became rounded; however, this rounding was not observed at low concentrations. Instead, low concentrations of all‐trans‐retinal increased the frequency of cAMP signaling during cell development.
Akiyama K, Tsuchihashi S, Morimoto YV.
europepmc +2 more sources
The Dictyostelium Centrosome [PDF]
The centrosome of Dictyostelium amoebae contains no centrioles and consists of a cylindrical layered core structure surrounded by a corona harboring microtubule-nucleating γ-tubulin complexes. It is the major centrosomal model beyond animals and yeasts.
Ralph Gräf+4 more
openaire +4 more sources
Luminal Phospholipase D Attacks Bacterial Membranes in Dictyostelium discoideum Phagosomes. [PDF]
This study shows that PldX, a luminal Phospholipase D, is necessary for the efficient destruction of ingested Klebsiella pneumoniae bacteria in Dictyostelium discoideum phagosomes. PldX and the AlyL lysozyme together attack the bacterial membrane and permeabilize it. To date, the molecular substrate of PldX remains to be determined. ABSTRACT Phagocytic
Lamrabet O+6 more
europepmc +2 more sources
The Cell Density Factor CMF Regulates the Chemoattractant Receptor cAR1 in Dictyostelium [PDF]
Starving Dictyostelium cells aggregate by chemotaxis to cAMP when a secreted protein called conditioned medium factor (CMF) reaches a threshold concentration.
Bishop, John D.,+2 more
core +12 more sources
Bacterial Survival in Dictyostelium [PDF]
We performed an assay to test the ability of different E. coli strains to survive inside amoebal cells after ingestion. In the assay we incubated bacteria together with cells of Dictyostelium discoideum for six hours. After co-incubation most of the uningested bacteria were removed by centrifugation and the remaining uningested bacteria were killed by ...
Christopher Rensing+10 more
openaire +4 more sources
Stochastic noise and synchronisation during Dictyostelium aggregation make cAMP oscillations robust [PDF]
The molecular network, which underlies the oscillations in the concentration of adenosine 3′, 5′-cyclic monophosphate (cAMP) during the aggregation phase of starvation-induced development in Dictyostelium discoideum, achieves remarkable levels of robust ...
Bates, Declan+3 more
core +11 more sources
An ancestral non-proteolytic role for presenilin proteins in multicellular development of the social amoeba dictyostelium discoideum [PDF]
Mutations in either of two presenilin genes can cause familial Alzheimer's disease. Presenilins have both proteolysis-dependent functions, as components of the γ-secretase complex, and proteolysis-independent functions in signalling.
Ahn+59 more
core +4 more sources
Monitoring Autophagy in Dictyostelium [PDF]
Autophagy is an intracellular degradation mechanism essential for cell survival and maintenance of cellular homeostasis, differentiation, and development. Recent research has highlighted the impact of autophagy in neurodegenerative diseases and aging.
Mesquita A+3 more
openaire +4 more sources
Village guards as “in between” in the Turkish-Kurdish conflict: Re-examining identity and position in intergroup conflict [PDF]
The current paper utilizes new approaches in intergroup conflict studies to examine the village guard system and its role in the Turkish-Kurdish conflict in Turkey.
Acar, Yasemin Gülsüm
core +2 more sources