Results 11 to 20 of about 5,995,584 (403)
Drosophila SOCS Proteins [PDF]
Journal of Signal Transduction, 2011 The importance of signal transduction cascades such as the EGFR and JAK/STAT pathways for development and homeostasis is highlighted by the high levels of molecular conservation maintained between organisms as evolutionary diverged as fruit flies and ...
W. Stec, M. Zeidler
semanticscholar +3 more sources
Peptidoglycan recognition proteins in Drosophila immunity. [PDF]
Developmental & Comparative Immunology, 2014 Innate immunity is the front line of self-defense against infectious non-self in vertebrates and invertebrates. The innate immune system is mediated by germ-line encoding pattern recognition molecules (pathogen sensors) that recognize conserved molecular patterns present in the pathogens but absent in the host.
S. Kurata
semanticscholar +4 more sources
Heat shock proteins and Drosophila aging [PDF]
Experimental Gerontology, 2011 Since their discovery in Drosophila, the heat shock proteins (Hsps) have been shown to regulate both stress resistance and life-span. Aging is characterized by increased oxidative stress and the accumulation of abnormal (malfolded) proteins, and these stresses induce Hsp gene expression through the transcription factor HSF.
J. Tower
semanticscholar +4 more sources
Protein Interactions on Telomeric Retrotransposons in Drosophila [PDF]
International Journal of Biological Sciences, 2012 Telomere length in Drosophila is maintained by targeted transposition of three non-LTR retrotransposons: HeT-A, TART and TAHRE (HTT), but understanding the regulation of this process is hindered by our poor knowledge of HTT associated proteins. We have identified new protein components of the HTT array: Chromator (Chro), the TRF2/DREF complex and the ...
Takács Sándor +4 more
openaire +5 more sources
Drosophila MCM protein complexes. [PDF]
Molecular Biology of the Cell, 1996 MCM genes encode a family of evolutionarily conserved proteins required for DNA replication. In Saccharomyces cerevisiae, where they were first identified, MCM genes interact genetically with each other. Allele specificity in these interactions suggests that MCM proteins physically associate with one another and that this association is essential for ...
Patrick H. O'Farrell +2 more
openaire +3 more sources
PLoS Biology, 2020 Proteins are typically denatured and aggregated by heating at near-boiling temperature. Exceptions to this principle include highly disordered and heat-resistant proteins found in extremophiles, which help these organisms tolerate extreme conditions such
Kotaro Tsuboyama +8 more
doaj +1 more source
Self-degradation of heat shock proteins [PDF]
, 1985 The 70-kDa heat shock protein of Drosophila decays in vivo at a much faster rate than other abundantly labeled proteins. Degradation also occurs in vitro, even during electrophoresis. It appears that this degradation is not mediated by a general protease
Buzin, Carolyn H. +2 more
core +1 more source
Genes & Development, 1989 The protein Elf-1 interacts with a cis-acting element that is required specifically for the neuronal expression of the Drosophila dopa decarboxylase gene Ddc. Using protein purified from Drosophila embryos, we raised Elf-1-specific monoclonal antibodies.
Sarah J. Bray +3 more
semanticscholar +1 more source
Frontiers in Oncology, 2013 Drosophila lacks telomerase and fly telomeres are elongated by occasional transposition of three specialized retroelements. Drosophila telomeres do not terminate with GC-rich repeats and are assembled independently of the sequence of chromosome ends ...
Grazia Daniela Raffa +3 more
doaj +1 more source
A novel human polycomb binding site acts as a functional polycomb response element in Drosophila. [PDF]
PLoS ONE, 2012 Polycomb group (PcG) proteins are key chromatin regulators implicated in multiple processes including embryonic development, tissue homeostasis, genomic imprinting, X-chromosome inactivation, and germ cell differentiation.
Suresh Cuddapah +6 more
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