Results 11 to 20 of about 114 (67)
Nucleic Acid-tagged Peptides: Encoding Libraries and Controlling Dimerization and Conformation
CHIMIA, 2013 Recent progress in the synthesis, screening, and self-assembly of nucleic acid–tagged peptidic libraries is reviewed.
Kalyan K. Sadhu, Nicolas Winssinger
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Quantification bias caused by plasmid DNA conformation in quantitative real-time PCR assay. [PDF]
PLoS ONE, 2011 Quantitative real-time PCR (qPCR) is the gold standard for the quantification of specific nucleic acid sequences. However, a serious concern has been revealed in a recent report: supercoiled plasmid standards cause significant over-estimation in qPCR ...
Chih-Hui Lin +2 more
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Protein-DNA interactions: statistical analysis of interatomic contacts in major and minor grooves
Вавиловский журнал генетики и селекции, 2018 The interactions between protein and DNA in essence underlie all processes in a living cell. Understanding the principles of specific recognition of DNA sites will open the way to understand how these processes are controlled and to interfere in their ...
A. A. Anashkina +5 more
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New Journal of Physics, 2013 We have observed the conformation-dependent electronic coupling between the monomeric subunits of a dinucleotide of 2-aminopurine (2-AP), a fluorescent analogue of the nucleic acid base adenine.
Julia R Widom +3 more
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Insights on the DNA Stability in Aqueous Solutions of Ionic Liquids
Frontiers in Bioengineering and Biotechnology, 2020 Deoxyribonucleic acid (DNA) carries the genetic information essential for the growth and functioning of living organisms, playing a significant role in life sciences research.
Teresa B. V. Dinis +2 more
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Microgels and apparatus for PAGE of nucleic acids in one or two dimensions
BioTechniques, 2018 We describe a system for horizontal 1D or 2D PAGE comprising an apparatus and microgels. There is no buffer outside the gel, making handling and sample loading easy.
Hans G Thormar +5 more
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T7 RNA polymerase functions in vitro without clustering. [PDF]
PLoS ONE, 2012 Many nucleic acid polymerases function in clusters known as factories. We investigate whether the RNA polymerase (RNAP) of phage T7 also clusters when active.
Kieran Finan +3 more
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IFITs: Emerging Roles As Key Anti-Viral Proteins
Frontiers in Immunology, 2014 Interferon-induced protein with tetratricopeptide repeats (IFITs) are a family of proteins which are strongly induced downstream of type I interferon (IFN) signaling.
Gregory I Vladimer +2 more
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First High-Resolution Crystal Structures of DNA:2′-O-Methyl-RNA Heteroduplexes
Crystals, 2022 Heteroduplexes composed of all-DNA and all-2′-OMe RNA strands do not occur in nature, but they have found application in the development of molecular beacons and could also be used as aptamers or elements of nucleic acid-based nanostructures that will ...
Rafał Dolot +3 more
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Use of Nucleic Acid Analogs for the Study of Nucleic Acid Interactions
Journal of Nucleic Acids, 2011 Unnatural nucleosides have been explored to expand the properties and the applications of oligonucleotides. This paper briefly summarizes nucleic acid analogs in which the base is modified or replaced by an unnatural stacking group for the study of ...
Shu-ichi Nakano +2 more
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