Results 11 to 20 of about 6,643 (277)

Simulated weightlessness procedure, head-down bed rest has reversible effects on the metabolism of rhesus macaque [PDF]

Molecular Brain
It is a consensus in the international manned space field that factors such as microgravity during the space flight can cause anxiety, depression and other important brain function abnormalities in astronauts.
Yuting Li, Xu Zhang, Zhen Xu, Xixia Chu, Zhiqiang Hu, Zhengyang Ye, Caiqin Li, Zhenbo Wang, Bin Zeng, Jingyu Pan, Qian Zhao, Chengbin Zhou, Zhaohui Lan, Guanghan Kan, Guang He, Xiaodan Xu, Weidong Li   +16 more
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Influence of Social Isolation During Prolonged Simulated Weightlessness by Hindlimb Unloading [PDF]

Frontiers in Physiology, 2019
The hindlimb unloading (HU) model has been used extensively to simulate the cephalad fluid shift and musculoskeletal disuse observed in spaceflight with its application expanding to study immune, cardiovascular and central nervous system responses, among
Candice G. T. Tahimic, Candice G. T. Tahimic, Amber M. Paul, Amber M. Paul, Ann-Sofie Schreurs, Ann-Sofie Schreurs, Samantha M. Torres, Samantha M. Torres, Linda Rubinstein, Linda Rubinstein, Sonette Steczina, Sonette Steczina, Moniece Lowe, Moniece Lowe, Sharmila Bhattacharya, Joshua S. Alwood, April E. Ronca, April E. Ronca, Ruth K. Globus   +18 more
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Müller cells are activated in response to retinal outer nuclear layer degeneration in rats subjected to simulated weightlessness conditions [PDF]

Neural Regeneration Research
A microgravity environment has been shown to cause ocular damage and affect visual acuity, but the underlying mechanisms remain unclear. Therefore, we established an animal model of weightlessness via tail suspension to examine the pathological changes ...
Yuxue Mu, Ning Zhang, Dongyu Wei, Guoqing Yang, Lilingxuan Yao, Xinyue Xu, Yang Li, Junhui Xue, Zuoming Zhang, Tao Chen   +9 more
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Fresh Gastrodia elata Blume alleviates simulated weightlessness-induced cognitive impairment by regulating inflammatory and apoptosis-related pathways [PDF]

Frontiers in Pharmacology, 2023
In aerospace medicine, the influence of microgravity on cognition has always been a risk factor threatening astronauts’ health. The traditional medicinal plant and food material Gastrodia elata Blume has been used as a therapeutic drug for neurological ...
Yiwen Zhang, Hong Huang, Caihong Yao, Xinran Sun, Qinghu He, Muhammad Iqbal Choudharyc, Shanguang Chen, Xinmin Liu, Xinmin Liu, Xinmin Liu, Ning Jiang   +10 more
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External to internal cranial perfusion shifts during simulated weightlessness: Results from a randomized cross-over trial [PDF]

npj Microgravity, 2023
The exact pathophysiology of the spaceflight-associated neuro-ocular syndrome (SANS) has so far not been completely elucidated. In this study we assessed the effect of acute head-down tilt position on the mean flow of the intra- and extracranial vessels.
Alessa L. Boschert, Peter Gauger, Anja Bach, Darius Gerlach, Bernd Johannes, Jens Jordan, Zhili Li, David Elmenhorst, Andreas Bauer, Karina Marshall-Goebel, Jens Tank, Jochen Zange, Jörn Rittweger   +12 more
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Tapping into rhythm generation circuitry in humans during simulated weightlessness conditions [PDF]

Frontiers in Systems Neuroscience, 2015
An ability to produce rhythmic activity is ubiquitous for locomotor pattern generation and modulation. The role that the rhythmogenesis capacity of the spinal cord plays in injured populations has become an area of interest and systematic investigation ...
Irina eSolopova, Victor eSelionov, Francesca eSylos Labini, Victor eGurfinkel, Francesco eLacquaniti, Yuri P Ivanenko   +5 more
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Impact of microgravity on retinal neuroimmune responses and visual dysfunction in rats [PDF]

International Journal of Ophthalmology
AIM: To analyze visual dysfunction in rats under simulated weightlessness (SW) by examining trans-laminar cribrosa pressure difference (TLCPD) and neuroimmune responses.
Jin-Shuo Liu, Nai-Qin Yan, Ying-Yan Mao, Chen Xin, Da-Peng Mou, Xin-Xiao Gao, Jia Guo, Ning-Li Wang, Si-Quan Zhu   +8 more
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Impacts of Simulated Weightlessness by Dry Immersion on Optic Nerve Sheath Diameter and Cerebral Autoregulation [PDF]

Frontiers in Physiology, 2017
Dry immersion (DI) is used to simulate weightlessness. We investigated in healthy volunteers if DI induces changes in ONSD, as a surrogate marker of intracranial pressure (ICP) and how these changes could affect cerebral autoregulation (CA).
Marc Kermorgant, Florian Leca, Nathalie Nasr, Nathalie Nasr, Marc-Antoine Custaud, Thomas Geeraerts, Thomas Geeraerts, Marek Czosnyka, Marek Czosnyka, Dina N. Arvanitis, Jean-Michel Senard, Jean-Michel Senard, Anne Pavy-Le Traon, Anne Pavy-Le Traon   +13 more
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Numerical analysis of blood flow in the abdominal aorta under simulated weightlessness and earth conditions [PDF]

Scientific Reports
Blood flow through the abdominal aorta and iliac arteries is a crucial area of research in hemodynamics and cardiovascular diseases. To get in to the problem, this study presents detailed analyses of blood flow through the abdominal aorta, together with ...
Marta Żyłka, Grzegorz Górski, Wojciech Żyłka, Agnieszka Gala-Błądzińska   +3 more
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Administration of Essential Phospholipids Prevents Drosophila Melanogaster Oocytes from Responding to Change in Gravity [PDF]

Cells
The aim of this study was to prevent initial changes in Drosophila melanogaster oocytes under simulated weightlessness and hypergravity at the 2 g level.
Ksenia K. Gogichaeva, Irina V. Ogneva
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