Novel Nucleotide Variations, Haplotypes Structure and Associations with Growth Related Traits of Goat AT Motif-Binding Factor () Gene [PDF]
Asian-Australasian Journal of Animal Sciences, 2015 The AT motif-binding factor (ATBF1) not only interacts with protein inhibitor of activated signal transducer and activator of transcription 3 (STAT3) (PIAS3) to suppress STAT3 signaling regulating embryo early development and cell differentiation, but is
Xiaoyan Zhang +7 more
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Identification and functional study of GATA4 gene regulatory variants in type 2 diabetes mellitus
BMC Endocrine Disorders, 2021 Background Type 2 diabetes mellitus (T2D) is a common and complex disease. Dysfunction of pancreatic β cells, which cannot release sufficient insulin, plays a central role in T2D. Genetics plays a critical role in T2D etiology. Transcription factor GATA4
Liangcai Ding +6 more
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Use of the Iron-Responsive RBT5 Promoter for Regulated Expression in Candida albicans
mSphere, 2022 Engineered conditional gene expression is used in appraisal of gene function and pathway relationships. For pathogens like the fungus Candida albicans, conditional expression systems are most useful if they are active in the infection environment and if ...
Yinhe Mao +5 more
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Genetic analysis of physical activity in twins [PDF]
The American Journal of Clinical Nutrition, 2005 The reduced contribution of physical activity (PA) to daily energy expenditure contributes to the increased prevalence of obesity. A genetic control of activity-induced energy expenditure (AEE) may contribute to a genetic susceptibility to obesity.Our aim was to investigate the relative contribution of genetic and environmental factors to the variation
Klaas R. Westerterp +3 more
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Astonishing advances in mouse genetic tools for biomedical research
Swiss Medical Weekly, 2015 The humble house mouse has long been a workhorse model system in biomedical research. The technology for introducing site-specific genome modifications led to Nobel Prizes for its pioneers and opened a new era of mouse genetics.
Walker Scot Jackson, Lech Kaczmarczyk
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Target identification strategies in plant chemical biology [PDF]
, 2014 The current needs to understand gene function in plant biology increasingly require more dynamic and conditional approaches opposed to classic genetic strategies.
Dejonghe, Wim, Russinova, Eugenia
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The Regulatory Roles of the Galactose Permease and Kinase in the Induction Response of the GAL Network in Saccharomyces cerevisiae [PDF]
, 2006 The GAL genetic switch of Saccharomyces cerevisiae exhibits an ultrasensitive response to the inducer galactose as well as the "all-or-none" behavior characteristic of many eukaryotic regulatory networks.
Hawkins, Kristy M., Smolke, Christina D.
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Genetic and Molecular Regulations of Neuronal Activity
International Journal of Molecular Sciences, 2023 This Special Issue of the International Journal of Molecular Sciences (IJMS) focuses on ‘Genetic and Molecular Regulations of Neuronal Activity’ [...]
Marcella Reale +3 more
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Gene-Drug Interaction in Stroke
Stroke Research and Treatment, 2011 Stroke is the third cause of mortality and one of most frequent causes of long-term neurological disability, as well as a complex disease that results from the interaction of environmental and genetic factors.
Serena Amici +3 more
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Distinct regions of the Swi5 and Ace2 transcription factors are required for specific gene activation [PDF]
, 1999 Swi5 and Ace2 are cell cycle-regulated transcription factors that activate expression of early G1-specific genes in Saccharomyces cerevisiae. Swi5 and Ace2 have zinc finger DNA-binding domains that are highly conserved, and the two proteins bind to the ...
McBride, Helen J. +2 more
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