Results 21 to 30 of about 456,743 (411)

Phoresis and Enhanced Diffusion Compete in Enzyme Chemotaxis [PDF]

open access: yesNano Lett. 2018, 18, 4, 2711-2717, 2021
Chemotaxis of enzymes in response to gradients in the concentration of their substrate has been widely reported in recent experiments, but a basic understanding of the process is still lacking. Here, we develop a microscopic theory for chemotaxis, valid for enzymes and other small molecules.
arxiv   +1 more source

Angiotensin-Converting Enzyme 2: SARS-CoV-2 Receptor and Regulator of the Renin-Angiotensin System

open access: yesCirculation Research, 2020
ACE2 (angiotensin-converting enzyme 2) has a multiplicity of physiological roles that revolve around its trivalent function: a negative regulator of the renin-angiotensin system, facilitator of amino acid transport, and the severe acute respiratory ...
Mahmoud Gheblawi   +8 more
semanticscholar   +1 more source

Identification of the SARS-CoV-2 Entry Receptor ACE2 as a Direct Target for Transcriptional Repression by Miz1

open access: yesFrontiers in Immunology, 2021
Multiple lines of evidence have demonstrated that cigarette smoke or Chronic Obstructive Pulmonary Disease upregulates angiotensin-converting enzyme 2, the cellular receptor for the entry of the severe acute respiratory syndrome coronavirus 2, which ...
Jing Yang   +7 more
doaj   +1 more source

A crucial role of angiotensin converting enzyme 2 (ACE2) in SARS coronavirus–induced lung injury

open access: yesNature Network Boston, 2005
During several months of 2003, a newly identified illness termed severe acute respiratory syndrome (SARS) spread rapidly through the world. A new coronavirus (SARS-CoV) was identified as the SARS pathogen, which triggered severe pneumonia and acute ...
K. Kuba   +23 more
semanticscholar   +1 more source

Indications for immediate angiotensin-converting enzyme inhibition in patients with acute myocardial infarction [PDF]

open access: yes, 1995
When initiated a few days after myocardial infarction, angiotensin-converting enzyme inhibition exerts beneficial effects on survival and morbidity in patients with asymptomatic left ventricular systolic dysfunction or symptomatic heart failure.
Hochman, Judith S.   +2 more
core   +1 more source

Angiotensin‐converting enzyme 2 (ACE2), SARS‐CoV‐2 and the pathophysiology of coronavirus disease 2019 (COVID‐19)

open access: yesJournal of Pathology, 2020
Angiotensin‐converting enzyme 2 (ACE2) has been established as the functional host receptor for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), the virus responsible for the current devastating worldwide pandemic of coronavirus disease 2019
A. Bourgonje   +12 more
semanticscholar   +1 more source

Angiotensin receptor blockers and risk of dementia: cohort study in UK Clinical Practice Research Datalink. [PDF]

open access: yes, 2014
AIMS: This was a cohort study to evaluate whether individuals exposed to angiotensin receptor blockers have a reduced risk of dementia compared with those exposed to angiotensin-converting enzyme inhibitors.
Bhaskaran, Krishnan   +5 more
core   +1 more source

An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels.

open access: yesJournal of Clinical Investigation, 1990
A polymorphism consisting of the presence or absence of a 250-bp DNA fragment was detected within the angiotensin I-converting enzyme gene (ACE) using the endothelial ACE cDNA probe. This polymorphism was used as a marker genotype in a study involving 80
B. Rigat   +5 more
semanticscholar   +1 more source

Nasal Gene Expression of Angiotensin-Converting Enzyme 2 in Children and Adults.

open access: yesJournal of the American Medical Association (JAMA), 2020
This study compares angiotensin-converting enzyme 2 (ACE2) gene expression, which has been associated with SARS-CoV-2 cell entry, in the nasal epithelium of children vs adults.
S. Bunyavanich, Anh N. Do, A. Vicencio
semanticscholar   +1 more source

The angiotensin converting enzyme and blood pressure in Jamaicans [PDF]

open access: yes, 1997
An insertion/deletion (I/D) polymorphism of the angiotensin I converting enzyme gene influences the level of serum angiotensin converting enzyme activity and has been associated with risk of several cardiovascular conditions.
Bennett, Franklyn I.   +7 more
core   +2 more sources

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