Results 21 to 30 of about 67,279 (165)
Нервно-мышечные болезни, 2020 Introduction. Atypical variants of chronic inflammatory demyelinating polyneuropathy are marked by its clinical heterogeneity and variable disease course.Aim of the study.
D. A. Grishina +2 more
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MR Images, Brain Lesions, and Deep Learning
Applied Sciences, 2021 Medical brain image analysis is a necessary step in computer-assisted/computer-aided diagnosis (CAD) systems. Advancements in both hardware and software in the past few years have led to improved segmentation and classification of various diseases.
Darwin Castillo +2 more
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RP-CARS reveals molecular spatial order anomalies in myelin of an animal model of Krabbe disease [PDF]
Journal of Biophotonics 10 (2017) 385-393, 2020 Krabbe disease (KD) is a rare demyelinating sphingolipidosis, often fatal in the first years of life. It is caused by the inactivation of the galactocerebrosidase (GALC) enzyme that causes an increase in the cellular levels of psychosine considered to be at the origin of the tissue-level effects.
arxiv +1 more source
Macrophages and Autoantibodies in Demyelinating Diseases [PDF]
Cells, 2021 Myelin phagocytosis by macrophages has been an essential feature of demyelinating diseases in the central and peripheral nervous systems, including Guillain–Barré syndrome (GBS), chronic inflammatory demyelinating polyneuropathy (CIDP), and multiple sclerosis (MS). The discovery of autoantibodies, including anti-ganglioside GM1 antibodies in the axonal
Haruki Koike, Masahisa Katsuno
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Atypical demyelinating disease [PDF]
Journal of Neurology, Neurosurgery & Psychiatry, 1974 A 17 year old girl died after an illness characterized by progressive mental deterioration and severe myoclonic jerks. Extensive pathological, virological, and immunological studies failed to support the diagnosis of subacute sclerosing panencephalitis but were compatible with disseminated demyelinating disease.
J. M. Adams +5 more
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Mechanisms and treatment strategies of demyelinating and dysmyelinating Charcot-Marie-Tooth disease
Neural Regeneration Research, 2023 Schwann cells, the myelinating glia of the peripheral nervous system, wrap axons multiple times to build their myelin sheath. Myelin is of paramount importance for axonal integrity and fast axon potential propagation.
Nadège Hertzog, Claire Jacob
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Journal of Clinical Pathology, 2006 A diagnosis of demyelination carries important therapeutic and prognostic implications. In most cases the diagnosis is made clinically, and involvement of the histopathologist is largely confined to postmortem confirmation and clinicopathological correlation.
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International Journal of General Medicine, 2021 Jian Li,1 Yi-Ming Zhao2 1Department of Neurology, Peking University Third Hospital, Beijing, 100191, People’s Republic of China; 2Center for Clinical Epidemiology, Peking University Third Hospital, Beijing, 100191, People’s Republic of ...
Li J, Zhao YM
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Frontiers in Cellular and Infection Microbiology, 2018 CXCL-1, also called keratinocyte-derived cytokine (KC), is a predominant chemokine produced in glial cells upon infection with Theiler's murine encephalomyelitis virus (TMEV).
Min H. Kang, Young H. Jin, Byung S. Kim
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Changes of statistical structural fluctuations unveils an early compacted degraded stage of PNS myelin [PDF]
Scientific Reports 4, 5430 (2014), 2013 Degradation of the myelin sheath is a common pathology underlying demyelinating neurological diseases from Multiple Sclerosis to Leukodistrophies. Although large malformations of myelin ultrastructure in the advanced stages of Wallerian degradation is known, its subtle structural variations at early stages of demyelination remains poorly characterized.
arxiv +1 more source