Results 21 to 30 of about 52,842 (247)
Cells, 2021 The social amoeba Dictyostelium discoideum provides an excellent model for research across a broad range of disciplines within biology. The organism diverged from the plant, yeast, fungi and animal kingdoms around 1 billion years ago but retains common ...
Robin S. B. Williams +6 more
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European Journal of Cell Biology, 2006 Annexins are a highly conserved ubiquitous family of Ca2+- and phospholipid-binding proteins present in nearly all eukaryotic cells. Analysis of the Dictyostelium genome revealed the presence of two annexin genes, the annexin C1 gene (nxnA) giving rise to two isoforms of 47 and 51 kDa (previously synexin), and the annexin C2 gene (nxnB) coding for a 56-
Rolf Müller +5 more
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Visualization of c-di-GMP in multicellular Dictyostelium stages
Frontiers in Cell and Developmental Biology, 2023 The bacterial signaling molecule cyclic diguanosine monophosphate (c-di-GMP) is only synthesized and utilized by the cellular slime mold Dictyostelium discoideum among eukaryotes.
Hayato Ide +3 more
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The role of the cortical cytoskeleton [PDF]
, 1996 We generated Dictyostelium double mutants lacking the two F-actin crosslinking proteins alpha-actinin and gelation factor by inactivating the corresponding genes via homologous recombination.
Albrecht, Richard +8 more
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Cooperative cell motility during tandem locomotion of amoeboid cells. [PDF]
, 2016 Streams of migratory cells are initiated by the formation of tandem pairs of cells connected head to tail to which other cells subsequently adhere. The mechanisms regulating the transition from single to streaming cell migration remain elusive, although ...
Bastounis, Effie +4 more
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Triparental inheritance in Dictyostelium [PDF]
Proceedings of the National Academy of Sciences, 2018 Sex promotes the recombination and reassortment of genetic material and is prevalent across eukaryotes, although our knowledge of the molecular details of sexual inheritance is scant in several major lineages. In social amoebae, sex involves a promiscuous mixing of cytoplasm before zygotes consume the majority of cells, but for technical ...
Gareth Bloomfield +4 more
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Dictyostelium discoideum as a non‐mammalian biomedical model
Microbial Biotechnology, 2021 Summary Dictyostelium discoideum is one of eight non‐mammalian model organisms recognized by the National Institute of Health for the study of human pathology. The use of this slime mould is possible owing to similarities in cell structure, behaviour and
Javier Martín‐González +2 more
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Current Issues in Molecular Biology, 2006 The 34 Mb genome of Dictyostelium discoideum is carried on 6 chromosomes and has been fully sequenced by an international consortium. The sequence was assembled on the classical and physical maps that had been built up over the years and refined by HAPPY mapping.
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Pteridines, 2017 Dictyostelium discoideum Ax2 is well-known for the synthesis of d-threo-tetrahydrobiopterin (DH4) with a smaller amount of l-erythro-tetrahydrobiopterin (BH4).
Kim Hye-Lim +2 more
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Cells, 2019 Dyskerin is a protein involved in the formation of small nucleolar and small Cajal body ribonucleoproteins. These complexes participate in RNA pseudouridylation and are also components of the telomerase complex required for telomere elongation.
Javier Rodriguez-Centeno +2 more
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