Cardiac hypertrophy and heart failure: from the case to review of literature [PDF]
In response to an increased workload due to physiological or pathological stimuli, the heart may undergo a process of growth with increased muscle mass called cardiac hypertrophy. It is a particular mechanism of long term compensation used by the heart
Massoni, Francesco +4 more
core +1 more source
Mechanisms of exercise-induced improvements in the contractile apparatus of the mammalian myocardium [PDF]
One of the main outcomes of aerobic endurance exercise training is the improved maximal oxygen uptake, and this is pivotal to the improved work capacity that follows the exercise training.
Adams +98 more
core +1 more source
Requirement of myomaker-mediated stem cell fusion for skeletal muscle hypertrophy
Fusion of skeletal muscle stem/progenitor cells is required for proper development and regeneration, however the significance of this process during adult muscle hypertrophy has not been explored.
Qingnian Goh, Douglas P Millay
doaj +1 more source
Micro-RNA family that modulates fibrosis and uses thereof [PDF]
The present invention relates to the identification of a microRNA family, designated miR-29a-c, that is a key regulator of fibrosis in cardiac tissue. The inventors show that members of the miR-29 family are down-regulated in the heart tissue in response
Olson, Eric N., van Rooij, Eva
core +1 more source
Comparison of upper body strength gains between men and women after 10 weeks of resistance training [PDF]
Resistance training (RT) offers benefits to both men and women. However, the studies about the differences between men and women in response to an RT program are not conclusive and few data are available about upper body strength response.
Bottaro, Martim +5 more
core +4 more sources
Sex differences in absolute and relative changes in muscle size following resistance training in healthy adults: a systematic review with Bayesian meta-analysis [PDF]
Background Muscle hypertrophy may be influenced by biological differences between males and females. This meta-analysis investigated absolute and relative changes in muscle size following resistance training (RT) between males and females and whether ...
Martin C. Refalo +5 more
doaj +2 more sources
Molecular brakes regulating mTORC1 activation in skeletal muscle following synergist ablation [PDF]
The goal of the current work was to profile positive (mTORC1 activation, autocrine/paracrine growth factors) and negative [AMPK, unfolded protein response (UPR)] pathways that might regulate overload-induced mTORC1 (mTOR complex 1) activation with the ...
Amy Patton +12 more
core +5 more sources
Effect of different sources of dietary protein on muscle hypertrophy in functionally overloaded mice
Dietary protein intake is important for skeletal muscle protein synthesis. In this study, we investigated the differential effect of protein sources on hypertrophy of plantaris muscle induced by surgical ablation of gastrocnemius and soleus muscles.
Shinya Aoyama +3 more
doaj +1 more source
Hypertrophy can be operationally defined as an increase in the axial cross-sectional area of a muscle fiber or whole muscle, and is due to increases in the size of pre-existing muscle fibers. Hypertrophy is a desired outcome in many sports.
Brad Schoenfeld +7 more
doaj +1 more source
Ventricular androgenic-anabolic steroid-related remodeling: an immunohistochemical study [PDF]
Background: Several fatal cases of bodybuilders, following a myocardial infarction after long exposure to androgenicanabolic steroids (AAS), are reported. In recent years, evidence has emerged of cases of heart failure related to AAS consumption, with no
Cecchi, Rossana +7 more
core +1 more source

