Results 21 to 30 of about 1,321,604 (332)

A model for a partnership of lipid transfer proteins and scramblases in membrane expansion and organelle biogenesis

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2021
The autophagy protein ATG2, proposed to transfer bulk lipid from the endoplasmic reticulum (ER) during autophagosome biogenesis, interacts with ER residents TMEM41B and VMP1 and with ATG9, in Golgi-derived vesicles that initiate autophagosome formation ...
A. Ghanbarpour   +3 more
semanticscholar   +1 more source

Organelle-targeted therapies: a comprehensive review on system design for enabling precision oncology

open access: yesSignal Transduction and Targeted Therapy, 2022
Cancer is a major threat to human health. Among various treatment methods, precision therapy has received significant attention since the inception, due to its ability to efficiently inhibit tumor growth, while curtailing common shortcomings from ...
Jingjing Yang   +3 more
semanticscholar   +1 more source

Characterisation of a novel cold‐adapted calcium‐activated transglutaminase: implications for medicine and food processing

open access: yesFEBS Open Bio, 2020
Transglutaminases are a family of enzymes that catalyse the cross‐linking of proteins by forming covalent bonds between lysine and glutamine residues in various polypeptides.
Rebeca Garcia Alvarez   +5 more
doaj   +1 more source

Organellar Evolution: A Path from Benefit to Dependence

open access: yesMicroorganisms, 2022
Eukaryotic organelles supposedly evolved from their bacterial ancestors because of their benefits to host cells. However, organelles are quite often retained, even when the beneficial metabolic pathway is lost, due to something other than the original ...
Miroslav Oborník
doaj   +1 more source

Organelle-specific autophagy in inflammatory diseases: a potential therapeutic target underlying the quality control of multiple organelles

open access: yesAutophagy, 2020
The structural integrity and functional stability of organelles are prerequisites for the viability and responsiveness of cells. Dysfunction of multiple organelles is critically involved in the pathogenesis and progression of various diseases, such as ...
R. Yao, C. Ren, Z. Xia, Yong-ming Yao
semanticscholar   +1 more source

Developmental regulation of an organelle tether coordinates mitochondrial remodeling in meiosis. [PDF]

open access: yes, 2018
Cellular differentiation involves remodeling cellular architecture to transform one cell type to another. By investigating mitochondrial dynamics during meiotic differentiation in budding yeast, we sought to understand how organelle morphogenesis is ...
Berchowitz, Luke   +5 more
core   +2 more sources

GetOrganelle: a fast and versatile toolkit for accurate de novo assembly of organelle genomes

open access: yesGenome Biology, 2018
GetOrganelle is a state-of-the-art toolkit to accurately assemble organelle genomes from whole genome sequencing data. It recruits organelle-associated reads using a modified “baiting and iterative mapping” approach, conducts de novo assembly, filters ...
Jianjun Jin   +6 more
semanticscholar   +1 more source

Mitochondrial and chloroplast stress responses are modulated in distinct touch and chemical inhibition phases [PDF]

open access: yes, 2016
Previous studies have identified a range of transcription factors that modulate retrograde regulation of mitochondrial and chloroplast functions in Arabidopsis (Arabidopsis thaliana).
De Clercq, Inge   +6 more
core   +2 more sources

Organelle by organelle [PDF]

open access: yesNature, 1975
The Cell in Medical Science. Vol. 1: The Cell and Its Organelles. Pp. xiii + 366. £7.80; $20.25. Vol. 2. Cellular Genetics, Development and Cellular Specialization. Pp. xvii + 597. £11.30; $29.25. Edited by F. Beck and J. B. Lloyd. (Academic: London and New York, January 1975.)
openaire   +1 more source

NOVOPlasty: de novo assembly of organelle genomes from whole genome data

open access: yesNucleic Acids Research, 2016
The evolution in next-generation sequencing (NGS) technology has led to the development of many different assembly algorithms, but few of them focus on assembling the organelle genomes.
Nicolas Dierckxsens   +2 more
semanticscholar   +1 more source

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