Results 21 to 30 of about 2,406,031 (343)
A mini-review of the diffusion dynamics of DNA-binding proteins: Experiments and models [PDF]
, 2020 In the course of various biological processes, specific DNA-binding proteins must find a particular target sequence/protein or a damaged site on the DNA efficiently. DNA-binding proteins perform this task based on diffusion. Yet, investigations over recent decades have found that the diffusion dynamics of DNA-binding proteins are generally complicated ...
arxiv +1 more source
CircGLIS3 Promotes High-Grade Glioma Invasion via Modulating Ezrin Phosphorylation
Frontiers in Cell and Developmental Biology, 2021 High-grade glioma is highly invasive and malignant, resistant to combined therapies, and easy to relapse. A better understanding of circular RNA (circRNA) biological function in high-grade glioma might contribute to the therapeutic efficacy.
Yan Li +10 more
doaj +1 more source
Specific protein-protein binding in many-component mixtures of proteins [PDF]
Physical Biology v1, 53 (2004), 2003 Proteins must bind to specific other proteins in vivo in order to function. The proteins must bind only to one or a few other proteins of the of order a thousand proteins typically present in vivo. Using a simple model of a protein, specific binding in many component mixtures is studied.
arxiv +1 more source
A Preclinical Study Comparing the Activity and Potency of OnabotulinumtoxinA and PrabotulinumtoxinA
Clinical, Cosmetic and Investigational Dermatology, 2023 David C Rupp, David Canty, Catherine Rhéaume, Birgitte Sondergaard, Celina Niño, Ron S Broide, Amy D Brideau-Andersen Allergan Aesthetics, an AbbVie Company, Irvine, CA, USACorrespondence: David C Rupp, Allergan Aesthetics, an AbbVie Company, 2525 Dupont
Rupp DC +6 more
doaj
Unraveling Hepcidin Plasma Protein Binding: Evidence from Peritoneal Equilibration Testing
Pharmaceuticals, 2019 Peptide hormone hepcidin regulates systemic iron metabolism and has been described to be partially bound to α2-macroglobulin and albumin in blood. However, the reported degree of hepcidin protein binding varies between <3% and ≈89%.
Laura E. Diepeveen +8 more
doaj +1 more source
Chemical Reviews, 2013 Arsenic is a trace element found in the earth’s crust at an average concentration of ∼5 μg/g (ppm). Although its relative abundance in the earth’s crust is about 54th, arsenic can become concentrated in some parts of the world because of natural mineralization. Arsenic is a component of 245 minerals, associated most frequently with other metals such as
Xing-Fang Li +4 more
openaire +3 more sources
Space Layout of Low-entropy Hydration Shells Guides Protein Binding [PDF]
arXiv, 2022 Protein-protein binding enables orderly and lawful biological self-organization, and is therefore considered a miracle of nature. Protein-protein binding is steered by electrostatic forces, hydrogen bonding, van der Waals force, and hydrophobic interactions.
arxiv
Protein folding and binding can emerge as evolutionary spandrels through structural coupling [PDF]
Proc Natl Acad Sci USA, 112:1797-1802, 2015, 2014 Binding interactions between proteins and other molecules mediate numerous cellular processes, including metabolism, signaling, and regulation of gene expression. These interactions evolve in response to changes in the protein's chemical or physical environment (such as the addition of an antibiotic), or when genes duplicate and diverge. Several recent
arxiv +1 more source
Photoaffinity Labeling of Plasma Proteins
Molecules, 2013 Photoaffinity labeling is a powerful technique for identifying a target protein. A high degree of labeling specificity can be achieved with this method in comparison to chemical labeling.
Masaki Otagiri, Victor Tuan Giam Chuang
doaj +1 more source
Frontiers in Pharmacology, 2023 Introduction: This study was performed to determine the levels of α1-acid glycoprotein (AGP) in old-age patients undergoing total hip arthroplasty. AGP is considered an acute phase protein produced during the acute phase reaction in the body to various ...
Muhammad Abbas +7 more
doaj +1 more source