Results 21 to 30 of about 51,369 (198)

Genetic insights on sleep schedules: this time, it's PERsonal. [PDF]

open access: yes, 2012
The study of circadian rhythms is emerging as a fruitful opportunity for understanding cellular mechanisms that govern human physiology and behavior, fueled by evidence directly linking sleep disorders to genetic mutations affecting circadian molecular ...
Chong, SY Christin   +2 more
core   +1 more source

Melatonin-related dysfunction in chronic restraint stress triggers sleep disorders in mice

open access: yesFrontiers in Pharmacology, 2023
Stress may trigger sleep disorders and are also risk factors for depression. The study explored the melatonin-related mechanisms of stress-associated sleep disorders on a mouse model of chronic stress by exploring the alteration in sleep architecture ...
Tian-Ji Xia   +12 more
doaj   +1 more source

Assaying locomotor activity to study circadian rhythms and sleep parameters in Drosophila. [PDF]

open access: yes, 2010
Most life forms exhibit daily rhythms in cellular, physiological and behavioral phenomena that are driven by endogenous circadian (≡24 hr) pacemakers or clocks. Malfunctions in the human circadian system are associated with numerous diseases or disorders.
Chiu, Joanna C   +4 more
core   +3 more sources

The role of melatonin in mood disorders [PDF]

open access: yes, 2015
Melatonin (N-acetyl-5-methoxytryptamine) has been discovered as a hormone secreted by the pineal gland, even though it is also synthetized in various other organs, tissues, and cells.
Cavuto, Marilde   +14 more
core   +1 more source

Nerve growth factor, brain-derived neurotrophic factor, and the chronobiology of mood: a new insight into the "neurotrophic hypothesis" [PDF]

open access: yes, 2015
The light information pathways and their relationship with the body rhythms have generated a new insight into the neurobiology and the neurobehavioral sciences, as well as into the clinical approaches to human diseases associated with disruption of ...
IANNITELLI, ANGELA   +2 more
core   +2 more sources

New and Emerging Approaches to Better Define Sleep Disruption and Its Consequences

open access: yesFrontiers in Neuroscience, 2021
Current approaches to quantify and diagnose sleep disorders and circadian rhythm disruption are imprecise, laborious, and often do not relate well to key clinical and health outcomes.
Bastien Lechat   +7 more
doaj   +1 more source

Therapeutics for Circadian Rhythm Sleep Disorders [PDF]

open access: yesSleep Medicine Clinics, 2010
The sleep-wake cycle is regulated by the interaction of endogenous circadian and homeostatic processes. The circadian system provides timing information for most physiological rhythms, including the sleep and wake cycle. In addition, the central circadian clock located in the suprachiasmatic nucleus of the hypothalamus has been shown to promote ...
Phyllis C. Zee, Ehren Dodson
openaire   +3 more sources

Circadian Rhythms, Sleep, and Disorders of Aging [PDF]

open access: yesTrends in Endocrinology & Metabolism, 2016
Sleep-wake cycles are known to be disrupted in people with neurodegenerative disorders. These findings are now supported by data from animal models for some of these disorders, raising the question of whether the disrupted sleep/circadian regulation contributes to the loss of neural function. As circadian rhythms and sleep consolidation also break down
Joanna Mattis, Amita Sehgal
openaire   +3 more sources

Chronobiology and Mood Disorders [PDF]

open access: yesPsikiyatride Güncel Yaklaşımlar, 2011
Living organizms show cyclic rhythmicity in a variety of physiological, hormonal, behavioral, and psychological processes. Sleep-wake cycles, body temperature, hormone levels, mood and cognition display a circadian rhythm in humans.
Yavuz Selvi   +2 more
doaj  

Diagnóstico dos transtornos do sono relacionados ao ritmo circadiano Diagnosis of circadian rhythm sleep disorders

open access: yesJornal Brasileiro de Pneumologia, 2008
Queixas de insônia e sonolência excessiva são comuns na investigação dos distúrbios respiratórios do sono; os transtornos do sono relacionados ao ritmo circadiano talvez sejam as causas mais freqüentemente esquecidas no diagnóstico diferencial destes ...
Denis Martinez   +2 more
doaj   +1 more source

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