Results 21 to 30 of about 170,096 (338)

Isolation and Pharmacological Characterization of α-Elapitoxin-Ot1a, a Short-Chain Postsynaptic Neurotoxin from the Venom of the Western Desert Taipan, Oxyuranus temporalis

Toxins, 2016
Taipans (Oxyuranus spp.) are elapids with highly potent venoms containing presynaptic (β) and postsynaptic (α) neurotoxins. O. temporalis (Western Desert taipan), a newly discovered member of this genus, has been shown to possess venom which displays ...
Carmel M. Barber, Muhamad Rusdi Ahmad Rusmili, Wayne C. Hodgson   +2 more
doaj   +1 more source

In vivo immunotherapy of lung cancer using cross-species reactive vascular endothelial growth factor nanobodies [PDF]

Iranian Journal of Basic Medical Sciences, 2017
Objective(s): Lung cancer is the main leading cause of cancer death worldwide. Angiogenesis is the main step in proliferation and spreading of tumor cells.
vFatemeh Kazemi-Lomedasht v, Kamran Pooshang-Bagheri, Mahdi Habibi-Anbouhi, Ensiyeh Hajizadeh-Safar, Delavar Shahbazzadeh, Hasan Mirzahosseini, Mahdi Behdani   +6 more
doaj   +1 more source

Isolation and Pharmacological Characterization of α-Elapitoxin-Oh3a, a Long-Chain Post-Synaptic Neurotoxin From King Cobra (Ophiophagus hannah) Venom

Frontiers in Pharmacology, 2022
The King Cobra (Ophiophagus hannah) is the world’s largest venomous snake and has a widespread geographical distribution throughout Southeast Asia. Despite proteomic studies indicating the presence of postsynaptic neurotoxins in O.
Tam M. Huynh, Anjana Silva, Anjana Silva, Geoffrey K. Isbister, Geoffrey K. Isbister, Wayne C. Hodgson   +5 more
doaj   +1 more source

Comparative Studies of the Venom of a New Taipan Species, Oxyuranus temporalis, with Other Members of Its Genus

Toxins, 2014
Taipans are highly venomous Australo-Papuan elapids. A new species of taipan, the Western Desert Taipan (Oxyuranus temporalis), has been discovered with two specimens housed in captivity at the Adelaide Zoo.
Carmel M. Barber, Frank Madaras, Richard K. Turnbull, Terry Morley, Nathan Dunstan, Luke Allen, Tim Kuchel, Peter Mirtschin, Wayne C. Hodgson   +8 more
doaj   +1 more source

Isolation and Characterization of Two Postsynaptic Neurotoxins From Indian Cobra (Naja Naja) Venom

Frontiers in Pharmacology, 2022
The Indian Cobra (Naja naja) is among the “Big Four” responsible for most of the snakebite envenoming cases in India. Although recent proteomic studies suggest the presence of postsynaptic neurotoxins in N.
Tam M. Huynh, Anjana Silva, Anjana Silva, Geoffrey K. Isbister, Geoffrey K. Isbister, Wayne C. Hodgson   +5 more
doaj   +1 more source

Development and characterization of single domain monoclonal antibody against programmed cell death ligand-1; as a cancer inhibitor candidate [PDF]

Iranian Journal of Basic Medical Sciences, 2022
Objective(s): One of the important interactions in controlling the human immune system is the reaction between checkpoint proteins such as programmed cell death-1 (PD-1) and its ligand, PD-L1.
Akbar Oghalaei, Feriedon Mahbudi, Fatemeh Rahimi Jamnani, Somayeh Piri-Gavgani, Fatemeh Kazemi-Lomedasht, Aida Hassanzadeh-Eskafi, Delavar Shahbazzadeh, Ahmad Adeli, Yeganeh Talebkhan, Mahdi Behdani   +9 more
doaj   +1 more source

Clinical effectiveness of hymenoptera venom immunotherapy [PDF]

, 2013
Treatment failure during venom immunotherapy (VIT) may be associated with a variety of risk factors. Our aim was to evaluate the association of baseline serum tryptase concentration (BTC) and of other parameters with the frequency of VIT failure during ...
Aberer, Werner, Biló, Maria Beatrice, Bodzenta-Lukaszyk, Anna, Bonifazi, Floriano, Campi, Paolo, Darsow, Ulf, Haeberli, Gabrielle, Hawranek, Thomas, Küchenhoff, Helmut, Lang, Roland, Müller, Ulrich, Przybilla, Bernhard, Quercia, Oliviero, Reider, Norbert, Ruëff, Franziska, Scheipl, Fabian, Schmid-Grendelmeier, Peter, Seitz, Michael J., Severino, Maurizio, Sturm, Gunter Johannes, Treudler, Regina, Wüthrich, Brunello   +21 more
core   +1 more source

Venoms : venomous animals and antivenomous serum-therapeutics

, 1908
A. Calmette, E. E. Austen
openalex   +6 more sources

Crotalus atrox venom preconditioning increases plasma fibrinogen and reduces perioperative hemorrhage in a rat model of surgical brain injury. [PDF]

, 2017
Perioperative bleeding is a potentially devastating complication in neurosurgical patients, and plasma fibrinogen concentration has been identified as a potential modifiable risk factor for perioperative bleeding.
Applegate, Richard, Bull, Brian S, Gren, Eric CK, Hay, Karen L, Hayes, William K, Kelln, Wayne, Kim, Cherine H, Lekic, Tim, McBride, Devin W, Raval, Ronak, Sherchan, Prativa, Tang, Jiping, Zhang, John H   +12 more
core   +1 more source

Moral Worth, Credit, and Non-Accidentality [PDF]

, 2020
This paper defends an account of moral worth. Moral worth is a status that some, but not all, morally right actions have. Unlike with merely right actions, when an agent performs a morally worthy action, she is necessarily creditworthy for doing the ...
Singh, Keshav
core   +1 more source