Results 31 to 40 of about 2,125 (132)

Treatment of bipolar disorder: a complex treatment for a multi-faceted disorder [PDF]

open access: yes, 2007
Background: Manic-depression or bipolar disorder (BD) is a multi-faceted illness with an inevitably complex treatment. Methods: This article summarizes the current status of our knowledge and practice of its treatment. Results: It is widely accepted that
A Cipriani   +180 more
core   +3 more sources

Drugs that lower the seizure threshold [PDF]

open access: yes, 2016
Drugs with potential to lower the seizure threshold are numerous and diverse. Whether they contribute to clinically overt seizures depends on the dosage in which they are taken, the time-course of their effects and the susceptibility of the patient ...
Alper   +48 more
core   +1 more source

Part 2: Drug Interactions Involving Cannabis Products in Persons Aged 18 and Over: A Summary of Published Case Reports and Analysis of the FDA Adverse Event Reporting System

open access: yesPharmacology Research &Perspectives, Volume 13, Issue 1, February 2025.
ABSTRACT The increasing utilization of cannabis products combined with lack of data regarding potential cannabis–prescription drug interactions is concerning. This study aimed to review published case reports and FDA Adverse Event Reporting System (FAERS) spontaneous reports to assess cannabis–drug interactions in persons aged 18 and over. A literature
Maryann R. Chapin   +7 more
wiley   +1 more source

Efficacy and safety of endoxifen in bipolar disorder: A systematic review

open access: yesHuman Psychopharmacology: Clinical and Experimental, Volume 39, Issue 4, July 2024.
Abstract Background Endoxifen, a protein kinase C inhibitor and selective estrogen receptor modulator, primarily used in breast cancer treatment, has recently emerged as a potential therapeutic option for managing manic episodes associated with bipolar disorder (BD).
Jithin Thekkelkuthiyathottil Joseph   +2 more
wiley   +1 more source

Cholinergic regulation of mood: from basic and clinical studies to emerging therapeutics. [PDF]

open access: yes, 2019
Mood disorders are highly prevalent and are the leading cause of disability worldwide. The neurobiological mechanisms underlying depression remain poorly understood, although theories regarding dysfunction within various neurotransmitter systems have ...
Dulawa, Stephanie C, Janowsky, David S
core  

Efficacy and safety of established and off‐label ADHD drug therapies for cognitive impairment or attention‐deficit hyperactivity disorder symptoms in bipolar disorder: A systematic review by the ISBD Targeting Cognition Task Force

open access: yesBipolar Disorders, Volume 26, Issue 3, Page 216-239, May 2024.
Abstract Background Abnormalities in dopamine and norepinephrine signaling are implicated in cognitive impairments in bipolar disorder (BD) and attention‐deficit hyperactivity disorder (ADHD). This systematic review by the ISBD Targeting Cognition Task Force therefore aimed to investigate the possible benefits on cognition and/or ADHD symptoms and ...
Kamilla W. Miskowiak   +27 more
wiley   +1 more source

Epilepsy and polycystic ovary syndrome: where is the link? [PDF]

open access: yes, 2006
Overrepresentation of polycystic ovary syndrome (PCOS) in women with epilepsy has been described since the early 1980s. While some authors attribute this association to an effect of the seizure disorder on the hypothalamic control of reproductive ...
L.Bilo, R.Meo
core   +1 more source

Patterns of pharmacotherapy for bipolar disorder: A GBC survey

open access: yesBipolar Disorders, Volume 26, Issue 1, Page 22-32, February 2024.
Abstract Objectives To understand treatment practices for bipolar disorders (BD), this study leveraged the Global Bipolar Cohort collaborative network to investigate pharmacotherapeutic treatment patterns in multiple cohorts of well‐characterized individuals with BD in North America, Europe, and Australia. Methods Data on pharmacotherapy, demographics,
Balwinder Singh   +44 more
wiley   +1 more source

Challenges in defining treatment‐resistant mania in adults: A systematic review

open access: yesBipolar Disorders, Volume 26, Issue 1, Page 7-21, February 2024.
Abstract Objectives To review the definitions of treatment‐resistant mania (TRM) in the literature and propose criteria for an operationalized definition. Methods A systematic search of five databases (MEDLINE, EMBASE, PsychInfo, Cochrane Central, and CINAHL) and data extraction of eligible articles. Results In total, 47 articles addressing the concept
Christina Gonzalez‐Torres   +5 more
wiley   +1 more source

Discovery Patterns of Drugs Approved for Treating Bipolar Disorder by Applying Operational Criteria of Serendipity: A Historical Analysis

open access: yesMental Illness, Volume 2024, Issue 1, 2024.
While the scientific community has long acknowledged the significant role of serendipity in shaping the field of contemporary psychopharmacology, its impact has not undergone a comprehensive analysis using operational methodologies. Serendipity, originally defined as discoveries stemming from a blend of luck and astuteness by Walpole, has been ...
Francisco López-Muñoz   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy