Results 31 to 40 of about 251,937 (291)
American Journal of Reproductive Immunology, Volume 89, Issue 1, January 2023., 2023 Abstract Background We investigated the effect of Erbu Zhuyu decoction (EBZY) on angiogenesis via uterine natural killer (uNK) cells and the PI3K/Akt/eNOS pathway in embryo implantation dysfunction (EID) mice. Methods Pregnant mice were randomly divided into blank, model, EBZY, progynova, and aspirin groups.
Mengmeng Shen +3 more
wiley +1 more source
Crosstalk between nitrite, myoglobin and reactive oxygen species to regulate vasodilation under hypoxia. [PDF]
PLoS ONE, 2014 The systemic response to decreasing oxygen levels is hypoxic vasodilation. While this mechanism has been known for more than a century, the underlying cellular events have remained incompletely understood.
Matthias Totzeck +3 more
doaj +1 more source
Bringing Nitric Oxide to the Molybdenum World—A Personal Perspective
Molecules, 2023 Molybdenum-containing enzymes of the xanthine oxidase (XO) family are well known to catalyse oxygen atom transfer reactions, with the great majority of the characterised enzymes catalysing the insertion of an oxygen atom into the substrate. Although some
Luisa B. Maia
doaj +1 more source
Nitrate Reductase Regulates Expression of Nitrite Uptake and Nitrite Reductase Activities in Chlamydomonas reinhardtii [PDF]
Plant Physiology, 1992 In Chlamydomonas reinhardtii mutants defective at the structural locus for nitrate reductase (nit-1) or at loci for biosynthesis of the molybdopterin cofactor (nit-3, nit-4, or nit-5 and nit-6), both nitrite uptake and nitrite reductase activities were repressed in ammonium-grown cells and expressed at high amounts in nitrogen-free media or in media ...
Jacobo Cárdenas +2 more
openaire +3 more sources
Nitrite Biosensing via Selective Enzymes—A Long but Promising Route
Sensors, 2010 The last decades have witnessed a steady increase of the social and political awareness for the need of monitoring and controlling environmental and industrial processes.
M. Gabriela Almeida +3 more
doaj +1 more source
Red blood cell endothelial nitric oxide synthase: A major player in regulating cardiovascular health
British Journal of Pharmacology, EarlyView., 2023 Abstract Red blood cells (RBCs) have traditionally been seen as simple carriers of gases and nutrients in the body. One important non‐canonical function of RBCs in the cardiovascular system is the regulation of nitric oxide (NO) metabolism. It has been shown that RBCs can scavenge NO, transport NO metabolites and produce NO in hypoxic conditions ...
Anthea LoBue +7 more
wiley +1 more source
Should the non‐canonical pathway of nitric oxide generation be targeted in hypertensive pregnancies?
British Journal of Pharmacology, EarlyView., 2023 Abstract Hypertension in pregnancy is prevalent, affecting around 10% of pregnancies worldwide, and significantly increases the risk of adverse outcomes for both mothers and their babies. Current treatment strategies for pregnant women with hypertension are limited, and new approaches for the management of hypertension in pregnancy are urgently needed.
Elizabeth C. Cottrell
wiley +1 more source
Nature Communications, 2020 Siroheme is an essential bacterial iron tetrapyrrole used by siroheme-dependent sulfite and nitrite reductases. Here the authors shed light on the catalytic mechanisms of siroheme synthase through the structures of the bifunctional dehydrogenase ...
Joseph M. Pennington +4 more
doaj +1 more source
Recent structural insights into the function of copper nitrite reductases.
Metallomics, 2017 Copper nitrite reductases (CuNiR) carry out the first committed step of the denitrification pathway of the global nitrogen cycle, the reduction of nitrite (NO2-) to nitric oxide (NO).
S. Horrell +3 more
semanticscholar +1 more source
Nitrite Reductase Activity of Cytochrome c [PDF]
Journal of Biological Chemistry, 2008 Small increases in physiological nitrite concentrations have now been shown to mediate a number of biological responses, including hypoxic vasodilation, cytoprotection after ischemia/reperfusion, and regulation of gene and protein expression. Thus, while nitrite was until recently believed to be biologically inert, it is now recognized as a potentially
Michael D. Font +7 more
openaire +3 more sources