Yeast Phosphoramidate-Adenosine Diphosphate Phosphotransferase [PDF]
Abstract An enzyme, phosphoramidate-ADP phosphotransferase, has been isolated from dried bakers' yeast. We have previously shown that phosphoramide, N-phosphorylglycine, and N-phosphohistidine can act as phosphate donors. Phosphoiodohistidine was shown also to function as a phosphate donor and the enzyme was stereospecific for the l form of this ...
Henry I. Nakada, Michael J. Dowler
openaire +2 more sources
The membrane bound N-terminal domain of human adenosine diphosphate ribosylation factor-1 (ARF1) [PDF]
The small G protein adenosine diphosphate ribosylation factor-1 (ARF1) is activated by cell membrane binding of a self-folding N-terminal domain. We present a model of the human ARF1 N-terminal peptide in planar lipid bilayers, determined from neutron ...
Amor+22 more
core +1 more source
ADMINISTRATION OF FRUCTOSE 1,6-DIPHOSPHATE DURING EARLY REPERFUSION SIGNIFICANTLY IMPROVES RECOVERY OF CONTRACTILE FUNCTION IN THE POSTISCHEMIC HEART [PDF]
Objectives: Fructose-1,6-diphosphate is a glycolytic intermediate that has been shown experimentally to cross the cell membrane and lead to increased glycolytic flux.
Cao-Danh, Hung+7 more
core +1 more source
Dynamics of Microtubule Growth and Catastrophe [PDF]
We investigate a simple model of microtubule dynamics in which a microtubule evolves by: (i) attachment of guanosine triphosphate (GTP) to its end at rate lambda, (ii) GTP converting irreversibly to guanosine diphosphate (GDP) at rate 1, and (iii) detachment of GDP from the end of a microtubule at rate mu.
arxiv +1 more source
Purinergic Signaling in Pulmonary Inflammation
Purine nucleotides and nucleosides are at the center of biologic reactions. In particular, adenosine triphosphate (ATP) is the fundamental energy currency of cellular activity and adenosine has been demonstrated to play essential roles in human ...
Thanh-Thuy T. Le+6 more
doaj +1 more source
The analysis of platelet aggregation in pregnant women with thrombophilia and burdened obstetric history was performed. It has been determined that the development of adverse effects of pregnancy is significantly influenced by conditions such as ...
Olha I. Zalyubovska+1 more
doaj +1 more source
rLOAD: does sex mediate the effect of acute antiplatelet loading on stroke outcome. [PDF]
BackgroundBiologic sex can influence response to pharmacologic therapy. The purpose of this proof-of-concept study was to evaluate the medicating effects of estrogen in the efficacy of acute antiplatelet loading therapy on stroke outcome in the rabbit ...
Compton, M Peggy+4 more
core +3 more sources
Dynamics of Microtubule Instabilities [PDF]
We investigate the dynamics of an idealized model of microtubule growth that evolves by: (i) attachment of guanosine triphosphate (GTP) at rate lambda, (ii) conversion of GTP to guanosine diphosphate (GDP) at rate 1, and (iii) detachment of GDP at rate mu. As a function of these rates, a microtubule can grow steadily or its length can fluctuate wildly.
arxiv +1 more source
TNB-738, a biparatopic antibody, boosts intracellular NAD+ by inhibiting CD38 ecto-enzyme activity
Cluster of differentiation 38 (CD38) is an ecto-enzyme expressed primarily on immune cells that metabolizes nicotinamide adenine dinucleotide (NAD+) to adenosine diphosphate ribose or cyclic ADP-ribose and nicotinamide.
Harshad S. Ugamraj+19 more
doaj +1 more source
Phosphoproteins and protein-kinase activity in isolated envelopes of pea (Pisum sativum L.) chloroplasts [PDF]
A protein kinase was found in envelope membranes of purified pea (Pisum sativum L.) chloroplasts. Separation of the two envelope membranes showed that most of the enzyme activity was localized in the outer envelope.
D.G. Robinson+17 more
core +1 more source