Results 41 to 50 of about 119,934 (290)

Quality of Life in Psoriasis Vulgaris: Use of the ItchyQoL Question­naire in a Secukinumab Phase III Trial in Patients with Psoriasis Vulgaris

Acta Dermato-Venereologica, 2019
Chronic pruritus is a bothersome symptom in psoriasis vulgaris and can profoundly reduce quality of life (QoL). In this exploratory analysis of the PSORITUS study, the impact of pruritus on QoL in 130 subjects with moderate-to-severe psoriasis was ...
Sonja Ständer, Sabine Steinke, Matthias Augustin, Dieter Metze, Karin Loser, Daniel Baeumer, Christian Sieder, Thomas Luger   +7 more
doaj   +1 more source

A Phase 3 Multicenter, Double‐Blind Study Comparing Efficacy, Safety, Immunogenicity, and Pharmacokinetics of Alkem's Biosimilar Teriparatide Versus Reference Teriparatide in Postmenopausal Osteoporosis

AGING MEDICINE, EarlyView.
This phase III study demonstrated that Alkem's biosimilar teriparatide is noninferior to reference teriparatide in improving bone mineral density at the lumbar spine and femoral neck in postmenopausal osteoporosis patients, with comparable safety, pharmacodynamics, and immunogenicity profiles over 48 weeks of treatment.
Nitin Kapoor, Thomas Paul, Rajeshwar Nath Srivastava, Saurabh Singh, Sunil Maheshwari, Vishal Patil, Awadhesh Kumar Yadav, Girish Bhatia, Sushil H. Mankar, Joe Joseph Cherian, Surabhi Maheshwari, Sudeepti Srivastava, Dattatray Pawar, Roshan Pawar, Amol Aiwale, Amitrajit Pal, Yogesh Rane, Vinayaka Shahavi, Akhilesh Sharma   +18 more
wiley   +1 more source

Usability of Validated Sleep-assessment Questionnaires in Patients with Chronic Pruritus: An Interview-based Study

Acta Dermato-Venereologica, 2018
Impaired sleep due to nocturnal pruritus is a common symptom in patients with chronic pruritus. However, there is no standardized, simplified instrument for assessing sleep-related problems in patients with chronic pruritus. After a literature search, we
Theresa Suilmann, Claudia Zeidler, Nani Osada, Claudia Riepe, Sonja Ständer   +4 more
doaj   +1 more source

Chronic Pruritus in the Absence of Skin Disease: A Retrospective Study of 197 French Inpatients

Acta Dermato-Venereologica, 2020
Chronic pruritus (CP) can occur in the absence of skin diseases, and may be secondary to various causes. The aim of this study was to retrospectively analyse the causes of CP without skin disease in a cohort of patients from the dermatology department ...
Marine Robert, Laurent Misery, Emilie Brenaut   +2 more
doaj   +1 more source

The Covert Surge: Murine Bile Acid Levels Are Associated With Pruritus in Pediatric Autoimmune Sclerosing Cholangitis

Frontiers in Pediatrics, 2022
ObjectivesThe exact etiology of pruritus in chronic cholestasis is unknown. Pruritus intensity does not correlate with common biochemical indices and there is a lack of biomarkers guiding diagnosis and treatment.
Katharina Meinel, Doloresz Szabo, Antal Dezsofi, Sina Pohl, Tanja Strini, Theresa Greimel, Victor Aguiriano-Moser, Harald Haidl, Martin Wagner, Axel Schlagenhauf, Jörg Jahnel   +10 more
doaj   +1 more source

Comparison between olanexidine gluconate and conventional antiseptics for surgical site infection in gastroenterological surgery: A meta‐analysis

Annals of Gastroenterological Surgery, EarlyView.
This meta‐analysis compared olanexidine gluconate (OLG) with conventional antiseptics on surgical site infections (SSIs) in gastroenterological surgery. OLG significantly reduced overall SSIs without statistical heterogeneity. Abstract Aim To compare the preventative effect of the new antiseptic olanexidine gluconate (OLG) with conventional antiseptics
Akihisa Matsuda, Takeshi Yamada, Kay Uehara, Aya Yamagishi, Hiroshi Yoshida   +4 more
wiley   +1 more source

Koebnerization of Hailey–Hailey disease into chronic prurigo nodularis: Clearance of both entities under a naloxone therapy

JEADV Clinical Practice
Hailey–Hailey disease (HHD) is a genetic skin disorder, accompanied by lesional pruritus and a relevant impact on quality of life of affected patients. Approved or even successful treatments are still lacking, highlighting the need for further insight in
Felix Witte, Dieter Metze, Sonja Ständer, Claudia Zeidler   +3 more
doaj   +1 more source

Cost-effectiveness and Quality of Specialized and Routine Care in a German Cohort of Patients with Chronic Pruritus

Acta Dermato-Venereologica, 2023
Chronic pruritus is a prevalent interdisciplinary symptom with a strong influence on health-related quality of life. Patients need extensive diagnostics and long-term treatment.
Svenja Müller, Sonja Ständer, Mandy Naatz, Matthias Augustin, Sabine Steinke   +4 more
doaj   +1 more source

Comparison of gabapentin and ketotifen in treatment of uremic pruritus in hemodialysis patients [PDF]

, 2016
Objectives: Uremic pruritus is a common problem in hemodialysis patients. Several treatments have been used for decreasing itching in these patients. Gabapentin and ketotifen are two drugs used for treating uremic patients.The aim of this study was to ...
Amirkhanlou, S., Hafezi, A.A., Parsaei, S., Rashedi, A., Taherian, J.   +4 more
core   +1 more source

Dupilumab for bullous pemphigoid with intractable pruritus [PDF]

, 2019
Bullous pemphigoid (BP) is an autoimmune blistering disorder that predominantly affects the elderly. Treatment regimens typically include topical and systemic immunosuppressive medications.
Eichenfield, Dawn Z, Orme, Charisse M, Seidman, Jason S   +2 more
core