Results 1 to 10 of about 53,334 (334)

Deoxyguanosine kinase deficiency and recurrent spontaneous pneumothorax: a case report

Journal of Medical Case Reports, 2023
Background Deoxyguanosine kinase deficiency is mainly manifested by hepatic and neurological damage, hence it belongs to the hepatocerebral form of mitochondrial deoxyribonucleic acid depletion syndrome.
Alice Ramboux, Alain Poncelet, Philippe Clapuyt, Isabelle Scheers, Etienne Sokal, Raymond Reding, Xavier Stephenne   +6 more
doaj   +1 more source

8-Fluoro-N-2-Isobutyryl-2′-Deoxyguanosine: Synthesis and Reactivity

Molbank, 2020
3′,5′-O-Bis(tert-butyldimethylsilyl)-8-fluoro-N-2-isobutyryl-2′-deoxyguanosine was synthesized from 3′,5′-O-bis(tert-butyldimethylsilyl)-N-2-isobutyryl-2′-deoxyguanosine by the treatment with N-fluorobenzenesulfonimide.
Andrei Solodinin, James Helmkay, Samuel Ollivier, Hongbin Yan   +3 more
doaj   +1 more source

Widely targeted metabolomics reveals the antioxidant and anticancer activities of different colors of Dianthus caryophyllus

Frontiers in Nutrition, 2023
Carnation is edible flower that has potent antioxidant properties and is used in traditional Chinese medicinal system and food industry. The phytochemicals responsible for these various proprieties, however, are not fully understood.
Xuhong Zhou, Xuhong Zhou, Miaomaio Wang, Hong Li, Shilong Ye, Wenru Tang   +5 more
doaj   +1 more source

Deoxyguanosine is a TLR7 agonist [PDF]

European Journal of Immunology, 2019
Abstract Toll‐like receptor 7 (TLR7) is an innate immune sensor for single‐strand RNA (ssRNA). Recent structural analysis revealed that TLR7 has an additional binding site for nucleosides such as guanosine, and is activated when both guanosine and ssRNA bind.
Davenne, Tamara, Bridgeman, Anne, Rigby, Rachel E., Rehwinkel, Jan   +3 more
openaire   +2 more sources

Incorporation characteristics of exogenous 15N-labeled thymidine, deoxyadenosine, deoxyguanosine and deoxycytidine into bacterial DNA.

PLoS ONE, 2020
Bacterial production has been often estimated from DNA synthesis rates by using tritium-labeled thymidine. Some bacteria species cannot incorporate extracellular thymidine into their DNA, suggesting their biomass production might be overlooked when using
Kenji Tsuchiya, Tomoharu Sano, Noriko Tomioka, Ayato Kohzu, Kazuhiro Komatsu, Ryuichiro Shinohara, Shinji Shimode, Tatsuki Toda, Akio Imai   +8 more
doaj   +1 more source

8-Oxo-7,8-Dihydro-2′-Deoxyguanosine (8-oxodG) and 8-Hydroxy-2′-Deoxyguanosine (8-OHdG) as a Potential Biomarker for Gestational Diabetes Mellitus (GDM) Development

Molecules, 2020
The growing clinical and epidemiological significance of gestational diabetes mellitus results from its constantly increasing worldwide prevalence, obesity, and overall unhealthy lifestyle among women of childbearing age. Oxidative stress seems to be the
Sandra K. Urbaniak, Karolina Boguszewska, Michał Szewczuk, Julia Kaźmierczak-Barańska, Bolesław T. Karwowski   +4 more
doaj   +1 more source

Mitosene-DNA adducts. Characterization of two major DNA monoadducts formed by 1,10-bis(acetoxy)-7-methoxymitosene upon reductive activation [PDF]

, 1997
Reductive activation of racemic 1,10-bis(acetoxy)-7-methoxymitosene WV15 in the presence of DNA, followed by enzymatic digestion and HPLC analysis, revealed the formation of various DNA adducts.
Duynhoven, John P.M. van, Gargiulo, Dario, Janssen, Lambert H.M., Maliepaard, Marc, Mol, Nico J. de, Reinhoudt, David N., Tomasz, Maria, Velzen, Ewoud J.J. van, Verboom, Willem   +8 more
core   +2 more sources

Photochemical pathways of 8-oxo-2′-deoxyguanosine under photodegradation

AIP Advances, 2022
The common product of an oxidatively damaged DNA, 8-oxo-2′-deoxyguanosine (8-oxo-dG), is known for photorepairing cyclobutane pyrimidine dimers. This study is to uncover the dynamics of 8-oxo-dG under photodegradation, which are poorly understood.
Terry Park, Ingu Lee, Seong-Jin Son, Youngbin Na, Do-Kyeong Ko   +4 more
doaj   +1 more source

OxiDIP-Seq for Genome-wide Mapping of Damaged DNA Containing 8-Oxo-2'-Deoxyguanosine

Bio-Protocol, 2022
8-oxo-7,8-dihydro-2′-deoxyguanosine (8-oxodG) is considered to be a premutagenic DNA lesion generated by 2'-deoxyguanosine (dG) oxidation due to reactive oxygen species (ROS).
Francesca Gorini, Giovanni Scala, Susanna Ambrosio, Barbara Majello, Stefano Amente   +4 more
doaj   +1 more source

Pyrimido[1,2-a]-purin-10(3H)-one, M(1)G, is less prone to artifact than base oxidation [PDF]

, 2005
Pyrimido[1,2-a]-purin-10(3H)-one (M(1)G) is a secondary DNA damage product arising from primary reactive oxygen species (ROS) damage to membrane lipids or deoxyribose.
Jeong, Yo-Chan, Nakamura, Jun, Swenberg, James A., Upton, Patricia B.   +3 more
core   +3 more sources