Results 1 to 10 of about 92,957 (356)
Mechanosensitivity of Human Oligodendrocytes [PDF]
Frontiers in Cellular Neuroscience, 2020 Oligodendrocytes produce and repair myelin, which is critical for the integrity and function of the central nervous system (CNS). Oligodendrocyte and oligodendrocyte progenitor cell (OPC) biology is modulated in vitro by mechanical cues within the magnitudes observed in vivo.
Daniela Espinosa-Hoyos +10 more
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Oligodendrocyte Development and Plasticity. [PDF]
Cold Spring Harbor Perspectives in Biology, 2016 Oligodendrocyte precursor cells (OPCs) originate in the ventricular zones (VZs) of the brain and spinal cord and migrate throughout the developing central nervous system (CNS) before differentiating into myelinating oligodendrocytes (OLs).
D. Bergles, W. Richardson
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How to make an oligodendrocyte [PDF]
Development, 2015 Oligodendrocytes produce myelin, an insulating sheath required for the saltatory conduction of electrical impulses along axons. Oligodendrocyte loss results in demyelination, which leads to impaired neurological function in a broad array of diseases ...
S. Goldman, Nicholas J. Kuypers
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The Pathobiology of the Oligodendrocyte [PDF]
Journal of Neuropathology and Experimental Neurology, 1997 Samuel K. Ludwin
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Oligodendrocytes in a Nutshell [PDF]
Frontiers in Cellular Neuroscience, 2015 Oligodendrocytes are the myelinating cells of the central nervous system (CNS). While the phrase is oft repeated and holds true, the last few years have borne witness to radical change in our understanding of this unique cell type. Once considered static glue, oligodendrocytes are now seen as plastic and adaptive, capable of reacting to a changing CNS.
John-Paul eMichalski +5 more
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Oligodendrocytes in Schizophrenia [PDF]
Schizophrenia Research and Treatment, 2011 Despite the many neuroimaging studies that suggest gray matter volume reductions in schizophrenia, there is no compelling postmortem evidence to suggest neuronal loss, nor is there a distinctive or specific signature of gray matter abnormalities in schizophrenia.
Vahram Haroutunian +3 more
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Cellular and Molecular Life Sciences, 2021 Oligodendrocyte precursor cells (OPCs) account for 5% of the resident parenchymal central nervous system glial cells. OPCs are not only a back-up for the loss of oligodendrocytes that occurs due to brain injury or inflammation-induced demyelination ...
J. Spaas +12 more
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The immunomodulatory oligodendrocyte [PDF]
Brain Research, 2016 Oligodendrocytes, the myelinating glial cells of the central nervous system (CNS), are due to their high specialization and metabolic needs highly vulnerable to various insults. This led to a general view that oligodendrocytes are defenseless victims during brain damage such as occurs in acute and chronic CNS inflammation.
Zeis, Thomas +2 more
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Neuron-Oligodendrocyte Interactions in the Structure and Integrity of Axons
Frontiers in Cell and Developmental Biology, 2021 The myelination of axons by oligodendrocytes is a highly complex cell-to-cell interaction. Oligodendrocytes and axons have a reciprocal signaling relationship in which oligodendrocytes receive cues from axons that direct their myelination, and ...
G. Duncan, Tyrell J Simkins, B. Emery
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Nature Neuroscience, 2020 Major depressive disorder (MDD) has an enormous impact on global disease burden, affecting millions of people worldwide and ranking as a leading cause of disability for almost three decades.
C. Nagy +13 more
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