Results 81 to 90 of about 1,801,761 (249)

Biallelic Inactivation of NSD1 Associated With Carcinogenesis in Sotos Syndrome

Pediatric Blood &Cancer, EarlyView.
Nicholas A. Borja, Anuja Sule, Katie Ann McMullen, Aditi Dhir, Matthew D. Hall, Heather J. McCrea, Sakir Humayun Gultekin, Mustafa Tekin, Bradley Gampel   +8 more
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Dual optical frequency comb using a multi-functional PIC based on fully integrated injection locked gain-switched lasers

Scientific Reports
The authors demonstrate and characterise a versatile photonic integrated circuit (PIC) that could serve as a mutually injection locked optical frequency comb (OFC), a 4-channel optical coherent transmitter or a dual optical frequency comb (DOFC).
Alejandro Rosado, M. Deseada Gutierrez-Pascual, Gaurav Jain, Frank Smyth, Prince M. Anandarajah   +4 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

An Approach to Nuclear Fusion Utilizing the Dynamics of High-Density Electrons and Neutrals, Part I

Plasma
An approach to achieve nuclear fusion utilizing the formation of high densities of electrons and neutrals is described. The abundance of low energy free electrons produces intense electric fields that reduce the Coulomb barrier in nuclear fusion ...
Alfred YiuFai Wong, Chun-Ching Shih
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Complete mitochondrial genome and phylogenetic analysis of Luciogobius parvulus (Synder, 1909) (Teleostei, Gobiidae) from Korea

Mitochondrial DNA. Part B. Resources
Luciogobius parvulus (Snyder, 1909) is distributed in restricted areas of Japan and South Korea. Here, we report the first complete mitochondrial genome of this species.
Min-Soo Kim, Philjae Kim, Shin Yu Sin, Jong-Wook Kim, Cheol-Woo Park, Su-Hyang Yoo, Jae-Goo Kim   +6 more
doaj   +1 more source

The role and implications of mammalian cellular circadian entrainment

FEBS Letters, EarlyView.
At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley   +1 more source

Nutritional treatment in patients with cardiovascular diseases, hepatic steatosis and metabolic disorders

Mìžnarodnij Endokrinologìčnij Žurnal
Background. Cardiovascular diseases remain the leading cause of death in both men and women in ­industrialized countries. They encompass a variety of conditions, including cerebrovascular disease, peripheral arterial disease, atherosclerosis, and deep ...
Fidel Krasniqi, Afrim Zeqiraj, Dafina Zeqiraj   +2 more
doaj   +1 more source