Results 101 to 110 of about 488,887 (308)

Prognosis of Long‐Term Continuous Renal Replacement Therapy and the Impact of Combined Continuous Intravenous Sodium Infusion Therapy

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Patients requiring long‐term continuous renal replacement therapy (CRRT) generally have poor prognoses. This study evaluated whether adding continuous intravenous sodium infusion (cIVNa) is associated with improved hemodynamics and outcomes in patients undergoing long‐term CRRT for ≥ 7 days.
Akinori Yamaguchi, Atsuyoshi Mita, Kosuke Sonoda, Makoto Harada, Koji Hashimoto, Hiroshi Imamura, Yuji Kamijo   +6 more
wiley   +1 more source

Establishing an Apheresis Medicine Program in a Resource‐Constrained Setting: A 5‐Year Experience From Lagos, Nigeria

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Establishing a comprehensive apheresis medicine program in a resource‐constrained setting presents significant structural, financial, and logistical challenges. Despite the growing clinical importance of apheresis services globally, published experience from sub‐Saharan Africa remains sparse.
Folasade Adelekan‐Popoola, Shakirat Gold‐Olufadi, Olufunto Olufela Kalejaiye, Abdullateef Ogala, Rasheed A. Balogun   +4 more
wiley   +1 more source

Synthesis and properties of O-beta-D-ribofuranosyl-(1''-> 2')-guanosine-5''-O-phosphate and its derivatives

, 2003
The efficient synthesis of O-beta-D-ribofuranosyl-(1"-2')-guanosine-5"-O-phosphate and O-beta-D-ribofuranosyl-(1"-->2')-adenosine-5"-O-phosphate, minor tRNA components, have been developed.
Efimtseva, E.V., Shelkunova, A.A., Herdewijn, Piet, Nauwelaerts, Koen, Lescrinier, Eveline, Mikhailov, S.N., Rozenski, Jef   +6 more
core   +1 more source

The Effect of Endothelin-1 on Gene Expression of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase via Transforming Growth Factor Beta (TGF–β) Receptor in Human Aortic Smooth Muscle Cells

مجله دانشکده پزشکی اصفهان, 2018
Background: Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (Nox) is one of the predominant sources of the production of free oxygen radicals in the vascular wall.
Parisa Dayati, Reyhaneh Niayesh-Mehr, Alireza Jafari, Hossein Babaahmadi-Rezaei   +3 more
doaj   +1 more source

Serum Myonectin Levels Are Positively Associated With Physical Function and Lower Frailty‐Related Limitation in Maintenance Hemodialysis Patients: A Cross‐Sectional Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Maintenance hemodialysis (MHD) patients frequently suffer from frailty, characterized by reduced physical function and poor prognosis. Myokines, such as myonectin, secreted by muscle, are emerging regulators of systemic health. This study investigated the relationship between serum myonectin, adipokines (adiponectin, omentin), and ...
Kenichi Kono, Yoshifumi Moriyama, Koji Ohashi, Naoya Otaka, Minako Tatsumi, Toyoaki Murohara, Noriyuki Ouchi, Satoru Oshima   +7 more
wiley   +1 more source

Hexose-6-Phosphate Dehydrogenase Contributes to Skeletal Muscle Homeostasis Independent of 11 beta-Hydroxysteroid Dehydrogenase Type 1

, 2011
Glucose-6-phosphate (G6P) metabolism by the enzyme hexose-6-phosphate dehydrogenase (H6PDH) within the sarcoplasmic reticulum lumen generates nicotinamide adenine dinucleotide phosphate (reduced) to provide the redox potential for the enzyme 11 beta ...
Jeyasuria, P, Keith L. Parker, Paul M. Stewart, Sherlock, Mark, Pancharatnam Jeyasuria, Mark Sherlock, Nina M. Semjonous, Stewart, Paul, Semjonous, Nina, Lavery, Gareth, Walker, Elizabeth, Parker, KL, Gareth G. Lavery, Elizabeth A. Walker   +13 more
core   +1 more source

Compatible solutes from hyperthermophiles improve the quality of DNA microarrays [PDF]

, 2007
Background: DNA microarrays are among the most widely used technical platforms for DNA and RNA studies, and issues related to microarrays sensitivity and specificity are therefore of general importance in life sciences.
Liu Chang-Gong, Volinia Stefano, Russo G, Evangelisti, R, Russo G., Marchesini Jlenia, Valentini Davide, Citterich, MH, Arcelli, D, Rossi S, Liu XP, Helmer Citterich M., Evangelisti Rita, Rita Evangelisti, ROSSI, Simona, Taccioli Cristian, Russo Giandomenico, Mauro Helmer Citterich, Croce, CM, Arcelli D, Chang-Gong Liu, Russo, G, MARCHESINI, Jlenia, Taccioli, C, Santos Jorge M, Arcelli Diego, Citterich MH, Liu CG, ARCELLI, Diego, Jlenia Marchesini, Croce CM, Liu Xiuping, Xiuping Liu, Nicoletta Mascellani, Marchesini, J, VALENTINI, Davide, MASCELLANI, Nicoletta, Giandomenico Russo, VOLINIA, Stefano, Davide Valentini, Mascellani Nicoletta, TACCIOLI, CRISTIAN, Evangelisti R, Volinia, S, Jorge M Santos, Volinia S., Valentini D, Cristian Taccioli, Simona Rossi, Mascellani N, Liu C. G., Rossi Simona, Liu X., Marchesini J, Santos J. M., Carlo M Croce, Stefano Volinia, Liu, CG, Diego Arcelli, CROCE, Carlo Maria, Helmer Citterich Mauro, Mascellani, N, Rossi, S, Valentini, D, Santos, JM, Liu, XP, Santos JM, Croce Carlo M, EVANGELISTI, Rita   +68 more
core   +1 more source

Comparative Evaluation of Hemodiafiltration, Hemoperfusion, and Standard Hemodialysis on Efficacy, Inflammatory Control, Dialysis Adequacy, and Safety in End‐Stage Renal Disease: A Prospective Observational Study

Therapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Background Chronic micro‐inflammation in patients with end‐stage renal disease (ESRD) is a significant driver of cardiovascular complications and diminished quality of life. While standard hemodialysis (SHD) effectively manages small‐molecule clearance, its ability to remove medium‐to‐large uremic toxins—the primary catalysts of systemic ...
Hongwei Zuo, Weisi Dai, Jie Mao, Mei Ye, Xingshan Lu, Xiaocui Zhang   +5 more
wiley   +1 more source

The fate of intracellular S1P regulates lipid droplet turnover and lipotoxicity in pancreatic beta-cells

Journal of Lipid Research
Lipotoxicity has been considered the main cause of pancreatic beta-cell failure during type 2 diabetes development. Lipid droplets (LD) are believed to regulate the beta-cell sensitivity to free fatty acids (FFA), but the underlying molecular mechanisms ...
Yadi Tang, Mariola Majewska, Britta Leß, Ilir Mehmeti, Philipp Wollnitzke, Nina Semleit, Bodo Levkau, Julie D. Saba, Gerhild van Echten-Deckert, Ewa Gurgul-Convey   +9 more
doaj   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source