Results 131 to 140 of about 1,209,776 (284)
Zhongshan Daxue xuebao. Yixue kexue ban, 2012 【目的】 研究分割剂量射线照射的宫颈癌Hela细胞表达肿瘤干细胞相关蛋白情况及裸鼠体内成瘤能力,探讨经此法富集宫颈癌肿瘤干细胞的可行性。【方法】 Hela细胞分组接受分割剂量分别为2、4、6、8、10及12 Gy的射线照射,总照射剂量24 ~ 42 Gy。流式细胞术检测各照射组及对照组细胞的ABCG2、CD44及CD133表达率;各组细胞接种裸鼠皮下,检测其体内成瘤能力。【结果】 各照射组细胞的ABCG2表达率均明显上调,以Hela-R2组(4 Gy×10次)细胞的表达率最高[(46.89±1.20)%]
doaj
Hvordan kan rektors blogg være en mediator for skoleutvikling?
, 2010 Bakgrunnen for denne oppgaven var den nye situasjonen med sosiale nettmedier og bruk av disse i skolen. Fokuset har vært på hvordan elever og lærere kan bruke disse i undervisningen, men siden forskning viser at rektor er helt sentral i innføringen av IKT i skolen, så valgte jeg å se på rektors bruk av ny teknologi og medium.
openaire +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2012 【目的】 探讨慢性阻塞性肺疾病(COPD) 患者动态肺过度充气与运动能力的关系。【方法】 对26例稳定期中重度COPD患者和12例健康人进行常规肺通气功能、弥散功能、肺容量和症状限制递增功率踏车心肺运动测试,在静息状态和运动过程中每隔1 min记录受试者潮式呼吸时流速容积曲线和深吸气量(IC)。【结果】 COPD 组在症状限制递增功率运动高峰时, IC(L)较静息状态下降(1.55 ± 0.46 vs 2.17 ± 0.50,P < 0.001); 运动高峰时ΔIC与摄氧量呈负相关 (r = -0 ...
doaj
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
ＳＢ２０２１９０对卡英酸诱导的癫痫大鼠模型认知功能的影响及机制
Zhongshan Daxue xuebao. Yixue kexue ban, 2014 摘 要：【目的】 研究ｐ３８丝裂原活化蛋白激酶（ｐ３８ＭＡＰＫ）选择性抑制剂ＳＢ２０２１９０对卡英酸（ＫＡ）致痫大鼠学习、记忆能力的影响及其与海马神经元凋亡的关系的探讨。【方法】４０只大鼠随机分为４组：假处理组、模型组和ＳＢ２０２１９０低、高剂量组（剂量分别为７．５ ｍｇ／ｋｇ，３０ ｍｇ／ｋｇ），对各组大鼠进行行为学观察，应用Ｍｏｒｒｉｓ水迷宫试验，检测大鼠学习和记忆能力，同时通过ＢＬ－４２０Ｆ生物机能实验系统描记脑电图的变化，采用 ＴＵＮＥＬ 检测细胞凋亡并计算凋亡率 ...
doaj
, 2010 Finanskrisen påviste alvorlige mangler i dagens bankregulering. Som en direkte årsak har Baselkomiteen for banktilsyn utgitt et forslag til nytt kapital- og likviditetsregelverk (Basel III), som skal forbedre banksektorens evne til å absorbere sjokk, og dermed redusere smitteeffekten til makroøkonomien.
openaire +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Design of Hybrid Excited Synchronous Machine for Electrical Vehicles [PDF]
, 2015 M. Wardach +4 more
core +1 more source