Results 161 to 170 of about 1,064,749 (319)
Zhongshan Daxue xuebao. Yixue kexue ban, 2014 摘 要： 【目的】 应用ＧｏｌｄｅｎｅｙｅＴＭ ２０Ａ扩增体系，讨论ＩＢＳ法和ＩＴＯ法在全同胞鉴定中的应用价值。【方法】 选取１５０对全同胞和５００对无关个体，用ＧｏｌｄｅｎｅｙｅＴＭ２０Ａ体系进行１９个常染色体ＳＴＲ基因座的扩增，计算状态一致性评分（ＩＢＳ），用ＩＴＯ法分别计算全同胞关系指数（ＦＳＩ）、半同胞关系指数（ＨＳＩ）及其比值（ＦＳＩ：ＨＳＩ）。【结果】 在检测ＧｏｌｄｅｎｅｙｅＴＭ ２０Ａ体系１９个基因座时，（１）当两个体的ＩＢＳ≥２２时，倾向于全同胞；当ＩＢＳ≤１３时，倾向于无关个体 ...
doaj
Diet Modification Alters Repeated Exposure Ethanol Tolerance Development. [PDF]
MicroPubl BiolRodriguez Borrero E +3 more
europepmc +1 more source
, 2014 Introduction: Childhood obesity is an important risk factor for the early cardiovascular disease. Studies show conflicting results on whether it is the diet or physical inactivity that play the most important role in treating childhood obesity and possible health consequences.
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Le retour d'expérience au service de l'innovation
, 2015 Ce texte a été écrit à la demande du Décanat de la Faculté des Sciences de l'Université de Genève afin de préciser le concept de « retour d'expérience » appliqué aux systèmes énergétiques. Ce concept est à la base des travaux effectués par le Groupe Systèmes Energétiques depuis 1978.
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FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2014 【目的】 采用RNA干扰(RNAi)技术阻断类风湿关节炎(RA)成纤维样滑膜细胞(FLS)尿激酶型纤溶酶原激活物受体(uPAR)基因的表达,探讨uPAR基因沉默后对RA-FLS功能产生的影响及有关机制?【方法】 收集行关节置换术或滑膜清理术的RA患者的滑膜组织,组织块法培养RA-FLS?通过阳离子脂质体转染的方法,转染体外合成的特异性uPAR-siRNA;利用荧光定量PCR法和Western blotting法检测uPAR沉默效果;CCK8法检测细胞增殖抑制率;流式细胞技术检测细胞周期改变 ...
doaj
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2014 【目的】 评价基于肾肿瘤影像解剖特征的RENAL评分系统临床应用的稳定性,并探讨该评分系统与局限性肾肿瘤患者术式选择的相关性?【方法】 回顾性分析2011年8月至2012年8月共225例在解放军总医院行手术治疗的局限性肾肿瘤患者的术前CT及临床资料,由三名影像科医师采用RENAL评分系统分别进行总分和R(最大径)?E(外生性/内生性)?N(与肾窦的距离)?A(腹/背侧)?L(沿肾纵轴的关系)和h(是否与肾蒂血管接触)各变量评分,采用统计学方法比较三名观察者评分的一致性?依据总评分将患者分为为低?中 ...
doaj
Identification and characterization of <i>Schizosaccharomyces pombe</i> splicing mutants. [PDF]
MicroPubl BiolNicholas LL +4 more
europepmc +1 more source
Hvordan kan rektors blogg være en mediator for skoleutvikling?
, 2010 Bakgrunnen for denne oppgaven var den nye situasjonen med sosiale nettmedier og bruk av disse i skolen. Fokuset har vært på hvordan elever og lærere kan bruke disse i undervisningen, men siden forskning viser at rektor er helt sentral i innføringen av IKT i skolen, så valgte jeg å se på rektors bruk av ny teknologi og medium.
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