Results 161 to 170 of about 1,209,776 (284)
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Glial overexpression of carbonic anhydrase <i>cah-4</i> promotes glial and systemic autophagy, and reduces polyglutamine aggregation in <i>C. elegans</i>. [PDF]
MicroPubl BiolWang L, Bianchi L.
europepmc +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 1994 对１９８７～１９９３年本校学者发表于国外期刊上的论著进行了统计与分析，并核对本校这几年在卫生部的中标课题，获卫生部科技进步奖的项目，说明这些论文在一定程度上反映了本校科研动态和学术成果。
doaj
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Overexpression of xanthine dehydrogenase extends lifespan in <i>C. elegans</i>. [PDF]
MicroPubl BiolChino A, Sugiyama A, Ohno H.
europepmc +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
An analysis of the bacterial and fungal diversity of the fecal material of gopher tortoises. [PDF]
MicroPubl BiolVankoningsveld LMK +2 more
europepmc +1 more source
Surgery before age 9 in patients with early onset spinal deformities: effects on thoracic dimensions
, 2009 Diméglio A +3 more
core +1 more source
Zhongshan Daxue xuebao. Yixue kexue ban, 2014 摘要： 【目的】 探讨人诱导多能干细胞（ｈｉＰＳ细胞）在体外向外周神经元分化的能力。【方法】人诱导多能干细胞在无饲养层培养条件下维持培养，然后在神经培养基中悬浮培养分化为神经球，通过把神经球贴壁在多聚赖氨酸和层粘连蛋白包被的培养板上，利用流式分选细胞方法获得神经嵴干细胞（ＮＣＳＣ），通过把神经嵴干细胞在外周神经诱导培养基中诱导分化，获得外周神经元，利用免疫荧光染色的方法检测神经嵴干细胞和外周神经元的标记物。【结果】贴壁的神经球出现特征性的神经花环（Ｎｅｕｒａｌ ｒｏｓｅｔｔｅｓ）结构 ...
doaj
Le retour d'expérience au service de l'innovation
, 2015 Ce texte a été écrit à la demande du Décanat de la Faculté des Sciences de l'Université de Genève afin de préciser le concept de « retour d'expérience » appliqué aux systèmes énergétiques. Ce concept est à la base des travaux effectués par le Groupe Systèmes Energétiques depuis 1978.
openaire +1 more source