Results 81 to 90 of about 3,486,813 (275)

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

open access: yesFEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas   +3 more
wiley   +1 more source

Earth system law: The juridical dimensions of earth system governance

open access: yesEarth System Governance, 2019
While the focus of earth system governance is on the human-social aspects of Earth system changes, law has played a peripheral part in the earth system governance scientific agenda.
Louis J. Kotzé, Rakhyun E. Kim
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Geo-neutrinos and Silicate Earth Enrichment of U and Th

open access: yes, 2010
The terrestrial distribution of U, Th, and K abundances governs the thermal evolution, traces the differentiation, and reflects the bulk composition of the earth.
Abe   +51 more
core   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

open access: yesMolecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla   +10 more
wiley   +1 more source

On the ballistic capture of asteroids for resource utilisation [PDF]

open access: yes, 2011
This paper investigates the concept of capturing in the Earth’s neighbourhood Earth-approaching objects such as asteroids and comets. These objects may provide access to potential resources, as well as be potential scientific mission opportunities.
McInnes, C.R., Sanchez Cuartielles, J.P.
core  

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Correction to the references Nurhasan OY et al (2006) and Tseng KH et al (2020)

open access: yesEarth, Planets and Space, 2021
Earth, Planets and Space
doaj   +1 more source

Cement stabilized red earth as building block and structural pavement layer [PDF]

open access: yesConstructii: Journal of Civil Engineering Research, 2014
Red Earth is most commonly used as material in the building and road construction. Many a times, the red earth found in various quarries is found not suitable for construction.
G.V. RAMA SUBBARAO, J. PURNA CHANDRA RAO
doaj  

Mapping Earth Analogs from Photometric Variability: Spin-Orbit Tomography for Planets in Inclined Orbits

open access: yes, 2012
Aiming at obtaining detailed information of surface environment of Earth analogs, Kawahara & Fujii (2011) proposed an inversion technique of annual scattered light curves named the spin-orbit tomography (SOT), which enables one to sketch a two ...
Borucki   +20 more
core   +1 more source

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