Results 151 to 160 of about 11,054,575 (256)

Antibiotic Therapy for Pyelonephritis in the Emergency Department. [PDF]

Emerg Med Australas
Yu J, Koolstra C, Smit V, Mitra B.
europepmc   +1 more source

Naloxone Does Not Modify the Hemodynamic and Neuroendocrine Effects of Clonidine in Normal Humans

, 1985
Roberto Pedrinelli, Gianpaolo Bernini, Antonio Salvetti   +2 more
openalex   +1 more source

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Loss of Skeletal Muscle Mass Is Associated With Reduced Cytotoxic T Cell Abundance and Poor Survival in Advanced Lung Cancer. [PDF]

J Cachexia Sarcopenia Muscle
Nie X, Sun Y, van Dijk DPJ, Deng M, Brecheisen R, Wang Z, Xia Q, Olde Damink SMW, Rensen SS.   +8 more
europepmc   +1 more source

Simultaneous inhibition of TRIM24 and TRIM28 sensitises prostate cancer cells to antiandrogen therapy, decreasing VEGF signalling and angiogenesis

Molecular Oncology, EarlyView.
TRIM24 and TRIM28 are androgen receptor (AR) coregulators which exhibit increased expression with cancer progression. Both TRIM24 and TRIM28 combine to influence the response of castrate‐resistant prostate cancer (CRPC) cells to AR inhibitors by mediating AR signalling, regulation of MYC and upregulating VEGF to promote angiogenesis. Castrate‐resistant
Damien A. Leach, Nilesh Chatterjee, Kellie Spahr, Gilberto Serrano de Almeida, Anabel Varela‐Carver, Taimur T. Shah, Mathias Winkler, Hashim U. Ahmed, Charlotte L. Bevan   +8 more
wiley   +1 more source

A Double-Edged Sword Perspective on Young Australians' Use of Social Media: A Structured Narrative Review. [PDF]

Health Promot J Austr
Salehi N, Marshall GR, Maziarfar MH, Zubrinich A, Madani N, Nickbakht M, Moustafa AA.   +6 more
europepmc   +1 more source

EMT‐associated bias in the Parsortix® system observed with pancreatic cancer cell lines

Molecular Oncology, EarlyView.
The Parsortix® system was tested for CTC enrichment using pancreatic cancer cell lines with different EMT phenotypes. Spike‐in experiments showed lower recovery of mesenchymal‐like cells. This was confirmed with an EMT‐inducible breast cancer cell line.
Nele Vandenbussche, Renske Imschoot, Béatrice Lintermans, Lode Denolf, Joachim Taminau, Charlotte Fieuws, Geert Berx, Kris Gevaert, Kathleen B. M. Claes   +8 more
wiley   +1 more source

Flexible Parametric Accelerated Failure Time Models With Cure. [PDF]

Biom J
Akynkozhayev B, Christoffersen B, Liu X, Humphreys K, Clements M.   +4 more
europepmc   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source

Estimands for Early-Phase Dose Optimization Trials in Oncology. [PDF]

Biom J
Mukherjee A, Moscovici JL, Liu Z.
europepmc   +1 more source