Results 211 to 220 of about 278,683,873 (354)

Skills in the UK: the long-term challenge : Leitch review of skills : interim report [PDF]

, 2005
Leitch, Sandy
core  

Respiratory complex I‐mediated NAD+ regeneration regulates cancer cell proliferation through the transcriptional and translational control of p21Cip1 expression by SIRT3 and SIRT7

Molecular Oncology, EarlyView.
NAD+ regeneration by mitochondrial complex I NADH dehydrogenase is important for cancer cell proliferation. Specifically, NAD+ is necessary for the activities of NAD+‐dependent deacetylases SIRT3 and SIRT7, which suppress the expression of p21Cip1 cyclin‐dependent kinase inhibitor, an antiproliferative molecule, at the translational and transcriptional
Masato Higurashi, Kazunori Mori, Hidetsugu Nakagawa, Momoko Uchida, Fumihiro Ishikawa, Motoko Shibanuma   +5 more
wiley   +1 more source

Temporal Associations of Physical Activity With Subsequent Knee Pain in Individuals With Knee Osteoarthritis: An Ecological Momentary Assessment Study. [PDF]

Eur J Pain
Chang AH, Hertel E, Bruun MK, Kristensen EM, Petersen KK, Rathleff MS.   +5 more
europepmc   +1 more source

Peripheral blood leukocyte signatures as biomarkers in relapsed ovarian cancer patients receiving combined anti‐CD73/anti‐PD‐L1 immunotherapy in arm A of the NSGO‐OV‐UMB1/ENGOT‐OV30 trial

Molecular Oncology, EarlyView.
Using mass cytometry, we analyzed serial blood samples from patients with relapsed epithelial ovarian cancer (EOC) treated with oleclumab–durvalumab combination immunotherapy in the NSGO‐OV‐UMB1/ENGOT‐OV30 trial. Our analysis identified potential predictive, monitoring, and response biomarkers detectable through liquid biopsy. These findings facilitate
Luka Tandaric, Annika Auranen, Katrin Kleinmanns, René DePont Christensen, Liv Cecilie Vestrheim Thomsen, Cara Ellen Wogsland, Emmet McCormack, Johanna Mäenpää, Kristine Madsen, Karen Stampe Petersson, Mansoor Raza Mirza, Line Bjørge   +11 more
wiley   +1 more source

Stable Isotope Reference Materials and Scale Definitions-Outcomes of the 2024 IAEA Experts Meeting. [PDF]

Rapid Commun Mass Spectrom
Camin F, Besic D, Brewer PJ, Allison CE, Coplen TB, Dunn PJH, Gehre M, Gröning M, Meijer HAJ, Hélie JF, Iacumin P, Kraft R, Krajnc B, Kümmel S, Lee S, Meija J, Mester Z, Mohn J, Moossen H, Qi H, Skrzypek G, Sperlich P, Viallon J, Wassenaar LI, Wielgosz RI.   +24 more
europepmc   +1 more source

Analysis of comprehensive genomic profiling of solid tumors with a novel assay for broad analysis in clinical diagnostics

Molecular Oncology, EarlyView.
In molecular cancer diagnostics, comprehensive genomic profiling (CGP) is going to replace the small NGS panels since it provides all clinically relevant somatic variants as well as genomic biomarkers with clinical value. Here, we compared two CGP assays and demonstrate that the choice for diagnostic implementation will depend on the specific ...
Guy Froyen, Pieter‐Jan Volders, Ellen Geerdens, Severine Berden, Joni Van der Meulen, Aaron De Cock, Stefanie Vermeire, Jacques Van Huysse, Marie de Barsy, Gabriela Beniuga, Wendy W. J. de Leng, Anne M. L. Jansen, Imke Demers, Zeliha Ozgur, Hendrikus Jan Dubbink, Ernst‐Jan M. Speel, Wilfred F. J. van IJcken, Brigitte Maes   +17 more
wiley   +1 more source

Comparative Analysis of Lysophosphatidic Acid Levels in Fibromyalgia and Other Painful Conditions in Female Patients. [PDF]

Eur J Pain
Menezes J, Jakobsson JE, Bersellini Farinotti A, Krock E, Hunt MA, Simon N, Venckute Larsson S, Tanum L, Kultima K, Kosek E, Svensson CI.   +10 more
europepmc   +1 more source

EFFECT OF NALOXONE ON LOSS OF CONSCIOUSNESS INDUCED BY I.V. KETAMINE

, 1985
Julie Amiot, Pierre Bouju, J.H. Palacci
openalex   +1 more source

Intravenous Naloxone in Acute Respiratory Failure [PDF]

, 1983
J. G. Ayres, Judith Rees, T. Lee, G.M. Cochrane   +3 more
openalex   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source