Results 61 to 70 of about 166,081,157 (256)
Triggering of the endorphin analgesic reaction by a cue previously associated with shock: Reversal by naloxone [PDF]
, 1979 Michael S. Fanselow, Robert C. Bolles
openalex +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
FEBS Letters, EarlyView.This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Unraveling Mycobacterium tuberculosis acid resistance and pH homeostasis mechanisms
FEBS Letters, EarlyView.Mycobacterium tuberculosis exhibits a remarkable resilience to acid stress. In this Review, we discuss some of the molecular mechanisms and metabolic pathways used by the tubercle bacilli to adapt and resist host‐mediated acid stress. Mycobacterium tuberculosis (Mtb) is a successful pathogen that has developed a variety of strategies to survive and ...
Janïs Laudouze +3 more
wiley +1 more source
FEBS Letters, EarlyView.The S1025 peptide is the major antidote to the YrzI toxin, which we renamed here as SpyT (Small Peptide YrzI Toxin) and SpyA (Small Peptide YrzI Antitoxin) (1). Degradation of the toxin–antitoxin spyTA mRNA, either by a translation‐dependent cleavage by the endoribonuclease Rae1 (2) or by direct attack by 3′‐exoribonucleases (3), also contributes to ...
Laetitia Gilet +4 more
wiley +1 more source
Canadian Medical Association Journal, 2018 Tina, Hu, Larry, Nijmeh, Adam, Pyle
openaire +2 more sources
Perfusion of Naloxone Through the Fourth Cerebral Ventricle Reverses the Circulatory and Hypnotic Effects of Halothane in Dogs [PDF]
, 1979 J. O. Arndt, Enno Freye
openalex +1 more source
FEBS Letters, EarlyView.α2 → 8 polysialic acid elicits poor immunogenicity. Small‐angle scattering shows a supramolecular structure with parallel‐chain binding, although in different forms at μm and mm calcium. The major histocompatibility complex requires molecular weights around 2000 Da to produce antibodies, and 2000 Da polysialic oligomers will bind in these structures ...
Kenneth A. Rubinson
wiley +1 more source
EFFECT OF MORPHINE AND NALOXONE ON PRIMING‐INDUCED AUDIOGENIC SEIZURES IN BALB/c MICE [PDF]
, 1976 Chia‐Shong Chen +2 more
openalex +1 more source
FEBS Letters, EarlyView.Venom peptides have shown promise in treating pain. Our study uses computer screening to identify a peptide that targets a sodium channel (NaV1.7) linked to chronic pain. We produced the peptide in the laboratory and refined its design, advancing the search for innovative pain therapies.
Gagan Sharma +8 more
wiley +1 more source
Primary afferent depolarisation of tooth pulp afferents is not affected by naloxone [PDF]
, 1978 James W. Hu +2 more
openalex +1 more source