Results 111 to 120 of about 5,769,861 (240)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
G-20-Gipfel in London: ein Durchbruch zur Regulierung der Finanzmärkte? [PDF]
, 2009 Reichen die auf dem G-20-Gipfel beschlossenen Maßnahmen aus, die Finanzmärkte zu regulieren und die Wahrscheinlichkeit zukünftiger Krisen zu senken? Für Rolf J.
Collier, Irwin +4 more
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Strengthening enterprise competitiveness by synchronizing supply chain
Business: Theory and Practice, 2011 When competition is fierce and many producers try to create a competitive advantage by lowering prices, price wars are very common, but only few survive. Low prices erode producers’ margins and economic viability of the company. Low prices are very short-
Rimvydas Jasinavičius +1 more
doaj
International regulatory cooperation after the crisis [PDF]
The heads of state of a broad coalition of nations, the Group of Twenty (G-20), met in September 2009 in Pittsburgh to chart the course of recovery from the financial crisis and set internationally agreed-upon objectives for the reform of regulatory ...
Richard Heckinger, Robert Steigerwald
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
, 2014 We predict the distinctive three dimensional space motions of hypervelocity stars (HVSs) and runaway stars moving in a realistic Galactic potential. For nearby stars with distances less than 10~kpc, unbound stars are rare; proper motions alone rarely ...
Bromley, Benjamin C. +3 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Problems of public sector accounting and financial reporting standards implementation into practice
Business: Theory and Practice, 2011 This article analyzes process of realization in practice and problems faced by accountants in implementation of Accounting and Financial Statement System Reform in the Public Sector which currently takes place in the European Union and other developed ...
Jovita Bikienė
doaj
Cumbre del G-20: ¿y después de Toronto? [PDF]
, 2010 ¿Qué ha supuesto la cumbre del G-20 de Toronto para la agenda de problemas de la economía global? El Marco para un Crecimiento sólido y equilibrado planteado en la cumbre del G-20 en Pittsburgh –que requería más ahorro y exportaciones para los países ...
Tugores Ques, Juan
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