Results 71 to 80 of about 930,467 (263)

Utilidade do PET/CT na caracterização do nódulo solitário pulmonar

Saúde & Tecnologia, 2011
Introdução – O cancro de pulmão/traqueia e brônquios é a principal causa de morte por neoplasia na União Europeia. A técnica de duas aquisições de imagem em tempos diferentes no Positron Emission Tomography/Computed Tomography (PET/CT) tem sido ...
Ana Graça, Lucia Garcia Bernardo, José Rafael Infante, Juan Rayo Madrid, Lina Vieira   +4 more
doaj   +1 more source

Linking neurogenesis, oligodendrogenesis, and myelination defects to neurodevelopmental disruption in primary mitochondrial disorders

FEBS Letters, EarlyView.
Mitochondrial remodeling shapes neural and glial lineage progression by matching metabolic supply with demand. Elevated OXPHOS supports differentiation and myelin formation, while myelin compaction lowers mitochondrial dependence, revealing mitochondria as key drivers of developmental energy adaptation.
Sahitya Ranjan Biswas, Porter L. Tomsick, Alicia M. Pickrell, Paul D. Morton   +3 more
wiley   +1 more source

Factores que influenciam a estabilidade da 18F-FDG

Saúde & Tecnologia, 2011
Introdução – A ausência de um ciclotrão para produção da 2-[18F]Flúor-2-deoxi-D-glucose (18F-FDG) é, actualmente, uma realidade para a maior parte dos centros onde se realizam exames de Tomografia por Emissão de Positrões (TEP),  sendo  importante ...
Ana Graça, Román Sánchez Sánchez, Lucía Garcia Bernardo, Juan Rayo Madrid, Filipa Lucena   +4 more
doaj   +1 more source

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Out-of- hospital mortality in the municipality of Cienfuegos, 2016

Medisur, 2020
Foundation: Mortality data indicate the number of deaths by place, time interval and cause. The evolution of this evidence is the combination of the problems characteristic of the populations living conditions and the conflicts of developing countries ...
Orlando Morera Álvarez, Daylin Madruga Jiménez, Liliana Caridad Romero Castro   +2 more
doaj  

Influence of operator’s professional experience and visual function in the myocardial perfusion scan semiautomatic processing: intra and inter operator variability in quantitative parameters estimation

Saúde & Tecnologia, 2016
Introduction – Myocardial perfusion scan (MPS) has an important role in the diagnosis, evaluation and follow-up of patients with coronary artery disease being the semiautomatic processing widely used for routine clinical practice.
Ana Sofia Reimão, Joana Pereira, Matina Nobre, Fábio Nascimento, Elisabete Carolino, Ilda Poças, Lina Vieira   +6 more
doaj   +1 more source

Modelado del comportamiento del combustible nuclear bajo irradiación mediante DIONISIO 2.0 [PDF]

, 2014
En este breve artículo se presenta la última versión de DIONISIO 2.0, un código de simulación del comportamiento del combustible nuclear bajo irradiación.
Denis, Alicia Catalina, Gonzalez, Martin Emilio, Lemes, Martín, Soba, Alejandro   +3 more
core  

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source

PET/CT with 18-fluor-fluorodeoxyglucose in the follow-up of the cutaneous malignant melanoma

Saúde & Tecnologia, 2015
Background – Cutaneous malignant melanoma (CMM) is one of the most lethal malignancies and the follow-up involves, in addition to clinical examination and analysis of tumor markers, several imaging methods such as the Positron Emission Tomography ...
Sofia Batanete, J. R. Infante, J. I. Rayo, Lina Vieira   +3 more
doaj   +1 more source

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source