Results 91 to 100 of about 3,194,804 (248)
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Le choix de l’école secondaire de langue française en Ontario par les parents
L’éducation représente une ressource centrale dans les nouvelles économies du savoir du XXIe siècle et la notion de choix scolaire est examinée ici dans le contexte de recomposition de l’État.
Nathalie Bélanger
doaj +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu +10 more
wiley +1 more source
Predicting academic achievement: The role of Motivation and Learning Strategies [PDF]
The aim of this study consists in testing a predictive model of academic achievement including motivation and learning strategies as predictors. Motivation is defined as the energy and the direction of behaviors; it is categorized in three types of ...
de la Iglesia, Guadalupe +3 more
core +2 more sources
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
La généralisabilité est un modèle statistique particulièrement adéquat quand il s’agit de mettre au point des dispositifs visant à évaluer des apprentissages.
Daniel Bain
doaj +1 more source
Participation, citoyenneté et éducation [PDF]
En los últimos años del siglo XX ha empezado a revitalizarse la ética de las virtudes al hilo de dos teorías ético-políticas que se proponen como alternativa al liberalismo dominante: el comunitarismo y el republicanismo.
Guichot Reina, Virginia
core +1 more source
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen +14 more
wiley +1 more source
This study was requested by a departmental firefighting and rescue school for firefighters in France. Based on ergonomics and professional didactics approaches, the aim is to analyze the activity of driving two emergency vehicles so to improve the ...
Christine Vidal-Gomel +2 more
doaj

