Results 121 to 130 of about 170,428 (263)

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

FEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura, Kengo Furuichi, Hiromitsu Akamatsu, Naoki Yamamoto, Sako Keisuke, Akihiko Koshino, Taichiro Minami, Megumi Oshima, Akinori Hara, Norihiko Sakai, Miho Shimizu, Kenta Takahashi, Minako Yamamura, Shin‐ichi Horike, Takiko Daikoku, Kenichi Harada, Yohei Shinmyo, Hiroshi Kawasaki, Takashi Wada, Yasunori Iwata   +19 more
wiley   +1 more source

ENJEUX DE L´ÉDUCATION DES ADULTES À L´ÉPOQUE CONTEMPORAINE: UNE APPROCHE CONCEPTUELLE

, 2017
International audienceDesafios de la educación de adultos en la época contemporánea. Una aproximación conceptualEste artículo presenta los más importantes desafíos de la educación de adultos en la época contemporánea. Estos desafíos se articulan en torno
Parra Salas, Doris
core   +1 more source

Lipopolysaccharide uptake is augmented in lipopolysaccharide‐tolerant mouse macrophage‐like cells via increased CD14 expression

FEBS Open Bio, EarlyView.
In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara, Takayuki Manabe, Mika Jouta, Kiyoshi Kawasaki   +3 more
wiley   +1 more source

Parcours d’avenir : l’atout d’une éducation à la française [PDF]

, 2014
Cet article présente la spécificité des lycées français à l’étranger, montrant comment se construit une forme d’identité culturelle plurielle chez les élèves.
Isabelle Marchi-Barbaux
core  

L’articulation théorie-pratique en éducation musicale. Apports de la psychologie cognitive

, 2015
International audienceThe discipline called music education develops practices (singing and listening) and conceptual knowledge. We make the assumption that while taking into account the sensitive at school, practical competences cannot be developed ...
Maizières, Frédéric, Odile Tripier-Mondancin, Tripier-Mondancin, Odile, Tricot, André, Frédéric Maizières, André Tricot   +5 more
core   +1 more source

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Small RNA pathways in mammalian oocytes

FEBS Open Bio, EarlyView.
Three distinct small RNA pathways operate in mammalian oocytes: RNAi interference (RNAi), the microRNA (miRNA) pathway, and the PIWI‐associated RNA (piRNA) pathway. These pathways use small RNAs to guide sequence‐specific repression and contribute to oocyte biology by targeting genes and mobile elements or appear insignificant since different ...
Petr Svoboda, Josef Pasulka
wiley   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Quelques problèmes de la recherche en éducation /

, 1990
Thème: L'alphabétisation et l'enseignement de base en Europe à la veille du XXIe siècle ; Bled, Yougoslavie, 9-12 octobre ...
Thomas, Rudolf, Conférence européenne des directeurs des institutions de recherche en matière d'enseignement (6e : 1992 : Bled, Yougoslavie). L'alphabétisation et l'enseignement de base en Europe à la veille du XXIe siècle, Conseil de l'Europe   +2 more
core  

L'évaluation des modules des formations de base à la Haute école pédagogique Vaud (Suisse) : que fait-on des résultats ? [PDF]

, 2014
Un nouveau dispositif d’évaluation des modules des formations de base dispensées à la Haute école pédagogique (HEP) Vaud (en Suisse) a été mis en oeuvre en 2011-2012.
Rovero, Philippe, Ricciardi Joos, Paola
core