Results 101 to 110 of about 170,428 (263)

Development of human monoclonal antibodies against TARM1 by yeast display

FEBS Open Bio, EarlyView.
Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe, Mayumi Saeki, Masaaki Hashiguchi, Sayaka Ono, Kazuhisa Aoki, Hidetaka Tanno   +5 more
wiley   +1 more source

Élargir la base du « paradigme des usages » pour appréhender les pratiques numériques : quelques éléments pour une approche renouvelée des études d'usages en éducation

, 2018
Les discours officiels des décideurs politiques industriels et des institutions éducatives n’ont de cesse de porter l’attention du grand public sur les ‘bienfaits’ du numérique en éducation, notamment pour développer l’autonomie des étudiants (Denouël ...
Brotcorne, Périne, Usages du numériques en éducation: regards critiques   +1 more
core  

La recherche en éducation médicale : état des lieux, perspectives et rôle de la Société internationale francophone d’éducation médicale (SIFEM)

, 2011
Contexte : Les pratiques de recherche en éducation médicale sont régulièrement mises en question dans le monde francophone, en raison de l’ancrage traditionnellement positiviste de la recherche bio-médicale qui influence considérablement les chercheurs ...
Jean-François Denef, Dory, Valérie, Valérie Dory, Pelaccia, Thierry, Denef, Jean-François, Thierry Pelaccia   +5 more
core   +1 more source

Quantitative proteomic analysis reveals different characteristics of bladder cancer cells after exposure to bisphenol A

FEBS Open Bio, EarlyView.
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu, Lanlan Li, Wenjuan Jia, Hanzhong Feng, Xiaoquan Yu, Youli Zhao, Fengzhi Yuan, Hui Ding, Junqiang Tian, Yong‐Xing He, Zhiping Wang   +10 more
wiley   +1 more source

Élaboration et évaluation d'activités d'éducation à la carrière dans les programmes de géographie et d'écologie de première secondaire

, 1999
La situation problématique de l'orientation scolaire et professionnelle des élèves du secondaire jumelée aux recommandations de différents groupes de travail en éducation pour la mise sur pied d'une école orientante, nous ont amené à élaborer ...
Huppé, Julie
core  

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

A educação repensada no contexto de pandemia da Covid-19

Revista de Educação PUC-Campinas
Este texto objetiva analisar como a Organização para a Cooperação e Desenvolvimento Econômico traz a insígnia da educação por meio do discurso da escolaridade interrompida em contexto de pandemia da COVID-19 e quais são as implicações na formação do ...
Andréia Aparecida Simão
doaj   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

L’éducation de base au Cambodge : un système en reconstruction

Revue Internationale d’Éducation de Sèvres, 2002
Erick Garnier, Gérard Renou
doaj   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source