Results 81 to 90 of about 248,335 (263)

Need-achievement, expectations and life purpose: A french-argentine study of PhDs in education [PDF]

, 2017
Here we present a comparative research study of doctoral programs in the social sciences in Argentina and France (2009-2017). The focus is to analyze professional pathways and their relationship to base, socio-cultural, psychosocial and structural ...
Aparicio, Miriam Teresita
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Professores do ensino superior: processos de desenvolvimento profissional e a base de conhecimentos para a docência

Revista Educação e Emancipação, 2014
O presente trabalho apresenta os resultados de uma pesquisa que buscou investigar os conhecimentos profissionais que fundamentam a prática pedagógica de professores que atuam no Ensino Superior.
Amali de Angelis Mussi
doaj  

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Perspectives sur l'utilisation des TI en éducation au Québec [PDF]

, 2014
Tiré de l'écran-titre (visionné le 27 juin 2017).Ce rapport identifie les tendances majeures dans le domaine de la technologie et des pratiques (l’infonuagique, les données, la mobilité et l’éducation ouverte), ainsi que les enjeux associés et les ...
Drouin, Pierre, Guay, Pierre-Julien, Ouimet, Marc, Parent, Marc-Antoine   +3 more
core  

La dimension linguistique des enjeux interculturels : de l’Éveil aux langues à l’éducation plurilingue [PDF]

, 2008
Nous traiterons dans cet article de la dimension linguistique des enjeux interculturels en questionnant la prise en compte de la diversité linguistique dans les milieux scolaires québécois.
Armand, Françoise, Dagenais, Diane, Nicollin, Laura   +2 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

O sistema nacional de educação narrado no documento base das conferências nacionais de educação/Conae e a gestão da escola contemporânea - The national education system narrated in the base document of national conferences on education/Conae and manage [PDF]

Revista de Gestão e Avaliação Educacional, 2015
Resumo Esta pesquisa analisa quais orientações, para a gestão democrática, inclusão e diversidade, nos oferece o documento base da Conferência Nacional de Educação/Conae na melhoria da gestão da escola pública contemporânea.
Ana Paula da Silva Pozzobon Castanho
doaj  

Organizational Memory: an Approach from Knowledge Management and Quality Management of Organizational Learning Perspectives [PDF]

The recognition of the fact that, as of late, knowledge represents one of the most important assets of an organization, decisively influencing its competitiveness, has led to some comprehensive approaches of organizational memory.
Ionut Anica-Popa, Liana Anica-Popa, Marinela Vrîncianu   +2 more
core  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source