Results 131 to 140 of about 3,429,334 (300)

La clarification des valeurs au cœur d’une éducation en vue d’un développement durable ? [PDF]

open access: yes, 2016
Traiter dans le cadre de la formation de questions socialement vives ou de problématiques de société complexes nous pousse souvent à proposer des actions concrètes, par exemple à trier les déchets ou à économiser le papier.
Pellaud, Francine
core  

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

L’éducation de base au Cambodge : un système en reconstruction

open access: yesRevue Internationale d’Éducation de Sèvres, 2002
Erick Garnier, Gérard Renou
doaj   +1 more source

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

open access: yesMolecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li   +10 more
wiley   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Políticas públicas de financiamento da educação no Brasil

open access: yesEccoS – Revista Científica, 2006
This article studies the main topics of the Brazilian education policies, especially the primary education financing. It is also commented the question of the public financing for Education, taking as base the Federal Constitution of 1988, the Lei de ...
João Cardoso Palma Filho
doaj  

A Educação Física na escolarização da pequena infância Physical Education in the Education of Infants

open access: yesPensar a Prática, 2006
Com a intenção de apresentar reflexões e proposições sobre a Educação Física na escolarização da criança de zero a seis anos apresentamos este estudo que se organiza em dois momentos distintos.
doaj   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

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