Results 101 to 110 of about 4,466,005 (254)

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

The evaluation of Râusor ski area (Retezat Mountains/Romania) in the context of becoming touristic resort for local interest [PDF]

open access: yesCinq Continents, 2012
L'évaluation du domaine skiable de Râuşor pour le déclarer ressort touristique d’intérêt local. Cette étude est destiné pour attirer l'attention sur le domaine skiable du notre pays.
OANA-ALINA LUPULESC
doaj  

Nutritional outcomes in HIV Exposed Infants in the Mingha Program, Dschang-Cameroon (2003-2011) [PDF]

open access: yes, 2015
Background: Prevention of Mother to Child Transmission (PMTCT) is a set of interventions that contribute in reducing the risk of HIV transmission from mother (parents) to the child. The infant feeding choice in the HIV context remains a key item of PMTCT.
Colizzi, Vittorio   +10 more
core   +1 more source

PICALM::MLLT10 translocated leukemia

open access: yesFEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen   +7 more
wiley   +1 more source

L’évaluation psycholinguistique de la parole chez les enfants d’âge préscolaire : un inventaire des outils francophones

open access: yesGlossa
Contexte. L’évaluation orthophonique repose sur des outils variés permettant d’objectiver les compétences des patients et de guider les décisions cliniques.
Julie Cattini   +2 more
doaj   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Le développement de la conscience de l’écrit chez l’enfant : standardisation et normalisation d’un outil d’évaluation

open access: yesGlossa
Contexte. Un bon développement des différentes composantes de la conscience de l’écrit est essentiel pour favoriser l’apprentissage de la lecture et de l’écriture chez l’enfant. Objectifs.
Anne Bragard   +3 more
doaj   +1 more source

A new 130nm F.E readout chip for microstrip detectors

open access: yes, 2009
In the context of the Silicon tracking for a Linear Collider (SiLC) R&D collaboration, a highly compact mixed-signal chip has been designed in 130nm CMOS technology intended to read Silicon strip detectors for the experiments at the future International ...
Comerma, Albert   +5 more
core   +1 more source

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