Results 41 to 50 of about 39,704 (219)
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Podium, 2021 The evaluation as a component of the teaching-learning process has the purpose of verifying the degree of fulfillment of the objectives formulated in the plans and study programs of Higher Education; this in turn constitutes a way for feedback and ...
Maribel Mola Cantero +2 more
doaj
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
Revisiting and Expanding Scriven's Fallacies About Formative and Summative Evaluation
Journal of MultiDisciplinary EvaluationThis article outlines the origins of the formative and summative evaluation and then revisits Scriven’s claims about eight fallacies. We add to seven further fallacies especially that there are such concepts as formative and summative assessment.
Janet Clinton, John Hattie
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Plaidoyer pour une évaluation formative à l’université et dans l’entreprise
Revue des Sciences Humaines, 2012 Cette contribution s’inscrit dans le cadre de l’élaboration d’une thèse de doctorat sur les opinions des évaluateurs algériens (à l’université et dans l’entreprise) quant à l’opération d’évaluation. A partir d’un état de la question, nous avons entrepris
Louiza BERROUHOU
doaj
Mesure et Évaluation en Éducation, 1995 Dans le domaine des soins infirmiers, les difficultés inhérentes à l’évaluation formative en milieu clinique sont vécues péniblement aussi bien par les enseignantes que par les élèves.
Denyse Langevin, Louise Bélair
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FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source