Results 121 to 130 of about 1,819,216 (267)
FEBS Open Bio, EarlyView.We analyzed alterations of PAR metabolism‐related proteins in PARG inhibitor‐resistant HCT116RPDD cells. Although PARG levels remained unchanged, HCT116RPDD cells exhibited reduced PARP1 and ARH3 expression and elevated PAR levels. Interestingly, HCT116RPDD cells exhibited slightly elevated intracellular NAD+/NADH and ATP levels. Our findings suggest a
Kaede Tsuda, Yoko Ogino, Akira Sato
wiley +1 more source
Metodologias de índices para análise da sustentabilidade em bacias hidrográficas. [PDF]
, 2016 A manutenção da quantidade e qualidade dos recursos hídricos é um desafio a ser equacionado na atualidade, tendo em vista que este recurso é indispensável para diversas formas de vida na terra.
CRUZ, M. A. S. +2 more
core
FEBS Open Bio, EarlyView.Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley +1 more source
Proyecto de elaboración de indices para medir la productividad de empresas del sector comercial especializadas en tiendas departamentales de moda [PDF]
, 2009 Desde el año 1919, el Ecuador ha dado acogida a un segmento muy particular en el sector comercial de la Economía, que ha dado cobertura a gran parte de las necesidades de los consumidores y consumistas pasando a formar parte fundamental y actualmente un ...
Cantos Proaño, Rosicler Ivon +2 more
core +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
Monitoreo espacio-temporal de la erosión hídrica en la cuenca de la Amazonía ecuatoriana
SiembraLa cuenca ecuatoriana del Amazonas, a pesar de su relieve mayormente plano o ligeramente ondulado y su densa cobertura vegetal, enfrenta un riesgo latente de degradación de los suelos debido a la erosión, ocasionada por factores como la deforestación ...
Javier Martín +4 more
doaj
FEBS Open Bio, EarlyView.The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida +6 more
wiley +1 more source
Estudios de Fonética Experimental, 2008 La electropalatografía (EPG) es, hoy en día, una de las herramientas más eficaces en el análisis instrumental articulatorio. Permite registrar los contactos de la lengua con el paladar a partir de la activación de los electrodos situados en la ...
doaj
Economic regimes identification using machine learning technics [PDF]
, 2018 43 páginas.Trabajo de Máster en Economía, Finanzas y Computación. Director: Dr. José Manuel Bravo Caro. Economic conditions over long time periods can be distinguished by regimes.
Caki, Mamed
core
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source