Results 101 to 110 of about 4,388,618 (289)

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

Sostenibilitat en el disseny, construcció i ús d'un edifici de vivendes a Barcelona [PDF]

open access: yes, 2010
A Europa, els edificis sostenibles concentren majors lloguers i majors taxes de creixement que els convencionals. Aquests edificis energèticament més eficients augmenten les seves tasses d’ocupació un 66% més per m2. No obstant a Espanya, la demanda d'
Peralta Romero, Arnau
core  

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

open access: yesMolecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris   +10 more
wiley   +1 more source

AN ASSESSMENT OF THEATRE EFFICIENCY IN AN AFRICAN TEACHING HOSPITAL [PDF]

open access: yesKanem Journal of Medical Sciences, 2017
Background: Operating theatre or operating room (OR in the US) is a designed facility where surgical operations take place. With an estimated 234 million operations performed yearly, and about half of its complications, of avoidable events, theatre ...
Babayo UD, Bello US
doaj  

Els serveis lingüístics en el paradigma 2.0 [PDF]

open access: yes, 2009
L’article descriu els aspectes tecnològics i socials relacionats amb el que s’ha denominat paradigma 2.0 com a model de treball en les organitzacions, i ho exemplifica amb diverses experiències directament aplicades al treball en els serveis ...
Estella Clota, Marta
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon   +9 more
wiley   +1 more source

Buidat dels continguts de la competència literària del currículum de llengua catalana i castellana de primària segons el Decret 142/2007 [PDF]

open access: yes, 2013
L'apartat del currículum de primària (Decret 142/2007) conté un apartat sota el títol d'Àmbit de llengües, dins del qual s'especifiquen tots els objectius, continguts i criteris d'avaluació que cal treballar per a cada un dels dicles d'educació primària.
Ambròs, Alba, Moreno, Anna M.
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

Ús d'una llengua electrònica en l'anàlisi de cervesa [PDF]

open access: yes, 2014
El Grup de Sensors i Biosensors de la UAB ha desenvolupat una llengua electrònica que permet analitzar i identificar diferents tipus de cerveses, així com estimar el seu grau alcohòlic. Aquest dispositiu és la combinació de sensors químics que simulen el
Valle Zafra, Manuel del
core   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

open access: yesMolecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee   +8 more
wiley   +1 more source

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