Results 111 to 120 of about 4,504,147 (220)
El Patrimoni arqueològic i el seu ús integrat
, 2001 Descripció de l’estat dels jaciments arqueològics de l’alta Garrotxa, i proposta d’establiment d’un Parc cultural de la regió, “com un espai on la conservació, l’estudi i l"ús integrat del patrimoni cultural es converteixin en unes eines eficaces per al ...
Saña Seguí, Maria, Alcalde, Gabriel
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Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Ús de recursos materials en l'educació matemàtica
, 2013 [cat] Aquest treball, titulat Ús de recursos materials en l’educació matemàtica, es fomenta en la importància que té innovar les metodologies emprades actualment pel professorat de matemàtiques, ja que avui dia el fracàs escolar en aquesta matèria és ...
Mayans Mayans, Verònica
core
ADP‐ribosylation: An emerging regulator of the epigenome
Molecular Oncology, EarlyView.ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho +2 more
wiley +1 more source
Total Antioxidant Activity in Normal Pregnancy
Online Journal of Health & Allied Sciences, 2009 Objective: Pregnancy is a state, which is more prone for oxidative stress. Various studies report development of a strong defence mechanisms against free radical damage, as the pregnancy progresses. Aim of our study is to assess the antioxidant status by
Adiga US, Adiga MNS
doaj
Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
UdG Llengua. Guia de la UdG per a un ús igualitari del llenguatge
, 2018 Aquesta guia és un extracte de la publicació 'UdG Llengua. Guia lingüística i d’estil', amb ISBN 978-84-8458-536-7 i dipòsit legal Gi.1890-2018Versió actualitzada de la guia per a un ús no sexista de la llengua i que forma part d’'UdG Llengua.
Universitat de Girona. Servei de Llengües Modernes
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Exploring Proximal and Distal Ultrasound-Guided Greater Occipital Nerve Block Approaches in Migraine: A Systematic Review and Meta-Analysis. [PDF]
Pain PractSabet H +9 more
europepmc +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source