Results 101 to 110 of about 4,504,147 (220)
Cancer‐associated mutations in endometriosis reframe a benign disease through molecular oncology
Molecular Oncology, EarlyView.This review aims to comprehensively analyse cancer‐associated somatic mutations (CAMs) present in endometriotic lesions, emphasizing their biological roles, spatial distribution and implications for translational applications in medicine. By contextualizing a benign state within a genomic framework, this analysis seeks to establish its value as a ...
Clarissa Mujacic +15 more
wiley +1 more source
Acte inaugural de la Jornada d' Agroterritori "Explotacions de vaca de llet de l'Euroregió"
, 2015 Acte d'inauguració del Seminari "Ús eficient de l'energia en explotacions de vaca de llet de l'Euroregió" a càrrec del Sr. Quim Meléndez, sostdirector de coordinació de l'Escola Politècnica Superior de la Universitat de Girona i del Sr.
Meléndez i Frigola, Joaquim +1 more
core +1 more source
, 2017 Anem a delimitar la noció de "paleta", la seua tipologia, funcionalitat i evolució en la història de la pintura. Establint alguns criteris bàsics en la disposició i mescla cromàtica.
Galbis Juan, Amparo +1 more
core
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
Com treure els guants d'un sol ús amb seguretat
, 2018 Projecte: La prevenció de riscos en la docència de la química experimental. PID: UB 2003Prevenció de riscos al laboratori químic: s'indica la forma de treure's els guants de laboratori d'un sol ...
Casamitjana i Badia, Núria +3 more
core
Molecular Oncology, EarlyView.This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu +3 more
wiley +1 more source
Ús obligatori de la mascareta [audiovisual]
, 2020 Coronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Ús; Mascaretes; Espais públics; Mesures de seguretatCoronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Uso; Mascarillas; Espacios públicos; Medidas de seguridadCoronavirus SARS-CoV-2; COVID-19; 2019-nCoV; Use; Masks;
core
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source