Cytotoxicity and α‐Amylase Inhibitory Activities of Limonoids From the Leaves of Azadirachta indica
Three new limonoids are isolated from Azadirachta indica leaves and structurally characterized. These compounds display significant, broad‐spectrum cytotoxicity against four human cancer cell lines. The most potent analogue, azadiraindin I, demonstrates strong potential as a lead for anticancer drug development.
Ying Yang, Yu‐Xin Yan, Ming‐Hua Qiu
wiley +1 more source
New Endiandric Acid from <i>Beilschmiedia lumutensis</i> and Their Molecular Docking Study as α-amylase and α-glucosidase Inhibitors. [PDF]
Saad NA +10 more
europepmc +1 more source
ABSTRACT Plasmodium vivax (P. vivax) malaria, once regarded as a comparatively benign infection, is increasingly recognized as a cause of severe, potentially life‐threatening multisystem disease. Concurrent secondary hemophagocytic lymphohistiocytosis (HLH), disseminated intravascular coagulation (DIC), and acute pancreatitis complicating P.
Tasnim Nafian +5 more
wiley +1 more source
Relation of Serum α-Amylase Level With Glycated Hemoglobin and Trace Elements in Patients With Diabetes Mellitus. [PDF]
Mahmud DA +5 more
europepmc +1 more source
Bioactive Compounds and Cytotoxicity of Seed and Leaf Oils of Moringa oleifera
Among the practical applications of the oils described in this study, their use as an ingredient in food stands out, as well as the potential for developing bioactive materials for packaging, conferring antioxidant and antimicrobial properties. Seed and leaf oils from Moringa oleifera exhibit functional properties of industrial interest and bioactive ...
Emanuela de Lima Viana +12 more
wiley +1 more source
Study on the Inhibitory Mechanisms of Native Cellulose, Microcrystalline Cellulose, and Soluble Cellodextrin on α-Amylase and Amyloglucosidase. [PDF]
Zhu Y +7 more
europepmc +1 more source
ABSTRACT Alcohol craving is a key process in alcohol abuse, especially during young adulthood, a period of heightened vulnerability and continued brain development. Although acute physical exercise has been proposed as a potential strategy to reduce craving and modulate affective and cognitive processes, current evidence remains limited regarding its ...
P. Sampedro‐Piquero +5 more
wiley +1 more source
Safety evaluation of an extension of use of the food enzyme α-amylase from the genetically modified <i>Bacillus licheniformis</i> strain NZYM-BC. [PDF]
EFSA Panel on Food Enzymes (FEZ) +15 more
europepmc +1 more source
Antidiabetic potential of a novel hydroxyphenyl-bi-benzopyran-hexol compound from Cassia fistula as an α-amylase inhibitor: Integrated in silico screening and in vitro validation using a nonlinear regression model. [PDF]
Baskar R +7 more
europepmc +1 more source
Synthesis of Some Novel Chalcone and 3,5-Disubstituted Pyrazoline Derivatives: Evaluation of Their α-Amylase and α-Glucosidase Inhibitory Activities In Vitro and In Silico. [PDF]
Erbay F +6 more
europepmc +1 more source

