Results 61 to 70 of about 1,038 (93)

α-Conotoxins active at α3-containing nicotinic acetylcholine receptors and their molecular determinants for selective inhibition. [PDF]

Br J Pharmacol, 2018
Cuny H, Yu R, Tae HS, Kompella SN, Adams DJ.   +4 more
europepmc   +1 more source

Neuronal Nicotinic Acetylcholine Receptor Modulators from Cone Snails. [PDF]

Mar Drugs, 2018
Abraham N, Lewis RJ.
europepmc   +1 more source

Correction to "Design, Synthesis, and Activity of an α-Conotoxin LtIA Fluorescent Analogue".

ACS Chemical Neuroscience
Yishuai Yang, Yao Tan, Dongting Zhangsun, Xiaopeng Zhu, S. Luo   +4 more
semanticscholar   +1 more source

Conotoxins targeting nicotinic acetylcholine receptors: an overview. [PDF]

Mar Drugs, 2014
Lebbe EK, Peigneur S, Wijesekara I, Tytgat J.   +3 more
europepmc   +1 more source

Structural and Functional Analyses of Cone Snail Toxins. [PDF]

Mar Drugs, 2019
Morales Duque H, Campos Dias S, Franco OL.   +2 more
europepmc   +1 more source

Therapeutic concentrations of varenicline in the presence of nicotine increase action potential firing in human adrenal chromaffin cells. [PDF]

J Neurochem, 2017
Hone AJ, Michael McIntosh J, Rueda-Ruzafa L, Passas J, de Castro-Guerín C, Blázquez J, González-Enguita C, Albillos A.   +7 more
europepmc   +1 more source

d-Amino Acid Substitution of α-Conotoxin RgIA Identifies its Critical Residues and Improves the Enzymatic Stability. [PDF]

Mar Drugs, 2019
Ren J, Zhu X, Xu P, Li R, Fu Y, Dong S, Zhangsun D, Wu Y, Luo S.   +8 more
europepmc   +1 more source

Shining a Light on Venom-Peptide Receptors: Venom Peptides as Targeted Agents for In Vivo Molecular Imaging. [PDF]

Toxins (Basel)
Chow CY, King GF.
europepmc   +1 more source

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Synthesis and evaluation of disulfide-rich cyclic α-conotoxin [S9A]TxID analogues as novel α3β4 nAChR antagonists

Bioorganic Chemistry, 2021
Head-to-tail cyclization is an effective strategy to improve the biological stability of peptides. The α-conotoxin [S9A]TxID is a peptide that inhibits α3β4 nAChR with high activity and selectivity.
Shuai Wang, Rui Li, Dongting Zhangsun
exaly   +2 more sources

Identification of nicotinic acetylcholine receptor subunits in different lung cancer cell lines and the inhibitory effect of alpha-conotoxin TxID on lung cancer cell growth

European Journal of Pharmacology, 2019
Lung cancer is an aggressive tumor with high incidence and mortality rate. There was growing evidence supporting that nicotinic acetylcholine receptors (nAChRs) play vital role inlung cancer development.
J. Qian, Yiqiao Liu, Zhihua Sun, Dongting Zhangsun, S. Luo   +4 more
exaly   +2 more sources