Results 121 to 130 of about 41,186 (264)

MOESM1 of A novel GH10 xylanase from Penicillium sp. accelerates saccharification of alkaline-pretreated bagasse by an enzyme from recombinant Trichoderma reesei expressing Aspergillus β-glucosidase

, 2017
Additional file 1: Figure S1. Multiple alignments and phygogenetic tree of PspXyn10, PspXyn10 orthologs and TrXyn3. (a) Multiple alignments of the PspXyn10, PspXyn10 orthologs and TrXyn3. The amino acid sequence of PspXyn10 was compared with those of endo-1,4-beta-xylanase from Penicillium brasilianum (OOQ87260), endo-1,4-beta-xylanase D from ...
Shibata, Nozomu, Suetsugu, Mari, Kakeshita, Hiroshi, Igarashi, Kazuaki, Hagihara, Hiroshi, Takimura, Yasushi   +5 more
openaire   +1 more source

Acarbose or Canagliflozin vs. Placebo to Ameliorate Post‐Bariatric Hypoglycaemia: The Clinical Outcomes of the HypoBar I Randomised Clinical Trial

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Treatment options for post‐bariatric hypoglycaemia (PBH) are empirical. We aimed to investigate the efficacy and safety of acarbose and canagliflozin for the treatment of PBH. Materials and Methods We performed a randomised, double‐blinded, cross‐over, placebo‐controlled clinical trial where placebo, acarbose 50 mg thrice daily, and ...
Carolina B. Lobato, Clara Tornøe Winding, Kirstine N. Bojsen‐Møller, Bolette Hartmann, Christoffer Martinussen, Simon Veedfald, Jens J. Holst, Sten Madsbad, Nils Bruun Jørgensen, Carsten Dirksen   +9 more
wiley   +1 more source

Comparison of SGLT2 Inhibitors for New‐Onset Proteinuria Risk in Patients With Type 2 Diabetes and Preserved Kidney Function

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To compare the effects of individual SGLT2 inhibitors on preventing new‐onset proteinuria in patients with type 2 diabetes and preserved kidney function. Materials and Methods A target trial emulation was performed using commercially available databases, including health checkups and claims data, between April 1, 2014 and March 31, 2023 ...
Hiroki Nobayashi, Michihiro Satoh, Takuo Hirose, Shingo Nakayama, Yutaro Iwabe, Hideaki Hashimoto, Takahisa Murakami, Kouji Okada, Takefumi Mori, Hirohito Metoki   +9 more
wiley   +1 more source

Synthesis of Some Novel Chalcone and 3,5‐Disubstituted Pyrazoline Derivatives: Evaluation of Their α‐Amylase and α‐Glucosidase Inhibitory Activities In Vitro and In Silico [PDF]

Arch Pharm (Weinheim)
A novel pyrazoline derivative (P2) was synthesized and demonstrated potent α‐glucosidase inhibition (IC50 = 2.10 µM), significantly surpassing acarbose and highlighting its promise as an effective oral antidiabetic agent. ABSTRACT This study reports the synthesis of some novel chalcone (C1–C3) and 3,5‐disubstituted pyrazoline derivatives (P1–P3 ...
Erbay F, Akatin M, Demir F, Kahriman N, Colak A, Ertunga N, Küçük M.   +6 more
europepmc   +2 more sources

Sex‐Specific Associations of Inflammatory Biomarkers With All‐Cause and Cardiovascular Mortality Across Glycaemic Status: A Prospective UK Biobank Study

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To explore sex‐specific heterogeneity in the prognostic discrimination of inflammatory markers for mortality across different glycaemic states. Methods This prospective cohort study included 450 438 participants from the UK Biobank (median follow‐up: 15.3 years), stratified by sex and glycaemic status.
Yawen Zhang, Menghan Li, Manrong Xu, Yun Shen, Lianxi Li, Gang Hu   +5 more
wiley   +1 more source

Dementia Risk in Type 1 and 2 Diabetes: A Nationwide Population‐Based Comparison

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Diabetes is increasingly recognised as a major contributor to cognitive decline and dementia, but the risk varies by diabetes type and treatment intensity. We compared the risk of all‐cause dementia, Alzheimer's disease (AD) and vascular dementia (VaD) among individuals with and without diabetes.
Ji Eun Jun, Seohyun Kim, In‐Kyung Jeong, Jae Hyeon Kim   +3 more
wiley   +1 more source

Reinventing henna: Enzyme‐catalysed colour release from stabilized Lawsonia inermis L. extracts

International Journal of Cosmetic Science, EarlyView.
The instability and reduced dyeing performance of a cosmetic formulation containing 2‐hydroxy‐1,4‐naphthoquinone (lawsone), derived from Lawsonia inermis L., is demonstrated in comparison to a novel two‐component system. This system comprises one formulation with naturally occurring lawsone precursors and a second containing a specific hydrolase ...
Nele Dallmann, Volkmar Vill, Fabian Straske   +2 more
wiley   +1 more source

Titration curves of cellulases fromTrichoderma reesei: demonstration of a cellulase-xylanase-β-glucosidase-containing complex [PDF]

FEMS Microbiology Letters, 1983
B. Sprey, C. Lambert
openaire   +1 more source

Glycemic control and renal function decline in patients with chronic coronary syndrome: A multicenter cohort study

Journal of Diabetes Investigation, EarlyView.
Achieving HbA1c of 6.5–6.9% is associated with a reduced risk of renal complications in patients with diabetes and chronic coronary syndrome. Abstract Aims/Introduction Diabetes mellitus significantly contributes to renal complications, especially in patients with coronary artery disease (CAD).
An‐Yu Cheng, Chin‐Chou Huang, Hsin‐Bang Leu, Wei‐Hsian Yin, Wei‐Kung Tseng, Yen‐Wen Wu, Tsung‐Hsien Lin, Hung‐I Yeh, Kuan‐Cheng Chang, Ji‐Hung Wang, Chau‐Chung Wu, Jaw‐Wen Chen   +11 more
wiley   +1 more source

Evaluation of %CV and average glucose derived from pre‐ and postprandial 6‐point glucose measurements for assessing hypoglycemia risk

Journal of Diabetes Investigation, EarlyView.
Six‐point pre‐ and postprandial glucose values were extracted from CGM to calculate average glucose and %CV. ROC analysis identified AG <167.7 mg/dL and %CV >21.6% as key risk factors, enabling simple detection of high hypoglycemia risk using limited glucose measurements. ABSTRACT Aims/Introduction This study determined the usefulness of coefficient of
Rika Soga, Keiichi Torimoto, Fumi Uemura, Yosuke Okada, Shingo Nakayamada   +4 more
wiley   +1 more source