Results 51 to 60 of about 1,798,291 (314)

Synthesis and α-Glucosidase Inhibitory Mechanisms of Bis(2,3-dibromo-4,5-dihydroxybenzyl) Ether, a Potential Marine Bromophenol α-Glucosidase Inhibitor

Marine Drugs, 2011
Bis(2,3-dibromo-4,5-dihydroxybenzyl) ether (BDDE), derived from the marine algae, is a potential α-glucosidase inhibitor for type 2 diabetes treatment.
Xiukun Lin, Jianteng Wei, Wei Zhang, Ming Liu   +3 more
doaj   +1 more source

MOESM6 of The putative β-glucosidase BGL3I regulates cellulase induction in Trichoderma reesei

, 2018
Additional file 6. Western blot analysis of BGL3I-his overexpressed in T. reesei QmU2â 3 using promoter pdc, xyn2 and cbh1. Western blot analysis of BGL3I-his in the intracellular protein extract (A) and in the culture supernatant (B) of BGL3I-his overexpressed transformants.
Zou, Gen, Jiang, Yanping, Liu, Rui, Zhu, Zhihua, Zhou, Zhihua   +4 more
openaire   +1 more source

Novel thiosemicarbazide-based β-carboline derivatives as α-glucosidase inhibitors: Synthesis and biological evaluation.

European journal of medicinal chemistry
In the quest for potent α-glucosidase inhibitors to combat diabetes, a series of novel thiosemicarbazide-based β-carboline derivatives (CTL1∼36) were synthesized and evaluated.
Bingwen Liang, Di Xiao, Shao-Hua Wang, Xuetao Xu   +3 more
semanticscholar   +1 more source

Honokiol as an α-glucosidase inhibitor

Frontiers in Pharmacology
Honokiol, a naturally occurring compound from Magnolia obovata Thunb., has many biological activities, but its anti-α-glucosidase activity is still unclear. Therefore, we determined its inhibitory effects against α-glucosidase.
Hua Zhu, Xin Zhong
doaj   +1 more source

Exploring synergistic inhibitory mechanisms of flavonoid mixtures on α-glucosidase by experimental analysis and molecular dynamics simulation.

Food Chemistry
The study was the first to evaluate the synergistic interaction of luteolin + quercetin, luteolin + 3-O-methylquercetin, and quercetin + 3-O-methylquercetin mixtures on α-glucosidase and the binding mechanisms were explored using both experimental and ...
Junkun Pan, Muhammad Nawaz, Jiechao Liu, Hui Liu, Zhenzhen Lv, Wenbo Yang, Zhonggao Jiao, Qiang Zhang   +7 more
semanticscholar   +1 more source

MOESM8 of The putative β-glucosidase BGL3I regulates cellulase induction in Trichoderma reesei

, 2018
Additional file 8. Oligonucleotides used in this study.
Zou, Gen, Jiang, Yanping, Liu, Rui, Zhu, Zhihua, Zhou, Zhihua   +4 more
openaire   +1 more source

FLAVONOIDS FROM RHYNCHOSIA PSEUDO-CAJAN AS SUITABLE α-GLUCOSIDASE INHIBITORS AND FREE RADICAL SCAVENGERS

International Research Journal of Pharmacy, 2014
A series of nine flavonoids , 1 - 9, isolated from Rhynchosia pseudo - cajan Cambe ss., ha s been investigated in present work for their biological potential against α - glucosidase, lipoxygenase (LOX), acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) enzymes ; and antioxidant activity against diphenylpicrylhydrazyl (DPPH) radica l ...
Muhammad Athar Abbasi, Ghulam Hussain, Aziz ur Rehman, Viqar Uddin Ahmad   +3 more
openaire   +1 more source

Selection and study of mutants ofDekkera intermediaandCandida wickerhamiiderepressed for β-glucosidase production [PDF]

FEMS Microbiology Letters, 1985
Mutants of Candida wickerhamii and Dekkera intermedia, derepressed for β-glucosidase biosynthesis, were isolated. These mutants were also shown to hyperproduce this enzyme. In anaerobic culture, the C. wickerhamii mutant still hyperproduced β-glucosidase and was derepressed. Glucose-cellobiose anaerobic fermentation by this strain was thus improved. On
Marc Leclerc, Bruno Blondin, Robert Ratomahenina, Alain Arnaud, Pierre Galzy   +4 more
openaire   +1 more source

Fluorinated indeno-quinoxaline bearing thiazole moieties as hypoglycaemic agents targeting α-amylase, and α-glucosidase: synthesis, molecular docking, and ADMET studies

Journal of Enzyme Inhibition and Medicinal Chemistry
Inhibition of α-glucosidase and α-amylase are key tactics for managing blood glucose levels. Currently, stronger, and more accessible inhibitors are needed to treat diabetes.
Nirvana A. Gohar, E. Fayed, Yousry A. Ammar, Ola A Abu Ali, A. Ragab, A. Mahfoz, Moustafa S. Abusaif   +6 more
semanticscholar   +1 more source

Bound Polyphenols from Red Quinoa Prevailed over Free Polyphenols in Reducing Postprandial Blood Glucose Rises by Inhibiting α-Glucosidase Activity and Starch Digestion

Nutrients, 2022
Inhibiting α-glucosidase activity is important in controlling postprandial hyperglycemia and, thus, helping to manage type-2 diabetes mellitus (T2DM). In the present study, free polyphenols (FPE) and bound polyphenols (BPE) were extracted from red quinoa
Yu Zhang, B. Bai, Yu Yan, J. Liang, Xiao-long Guan   +4 more
semanticscholar   +1 more source