Results 171 to 180 of about 41,186 (264)

Comparative effectiveness of combination therapy with SGLT‐2 inhibitors and GLP‐1 RAs compared with SGLT‐2 inhibitors in individuals with type 2 diabetes: A prevalent new‐user cohort study

Diabetes, Obesity and Metabolism, Volume 28, Issue 4, Page 3273-3284, April 2026.
Abstract Aims To evaluate the effectiveness of combination therapy with sodium‐glucose cotransporter 2 (SGLT‐2) inhibitors and glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) compared with continued SGLT‐2 inhibitor therapy in routine practice among individuals with type 2 diabetes.
Gregor A. Maier, Beata Hennig, Wolfgang Rathmann, Oliver Kuss   +3 more
wiley   +1 more source

Structural and computational supported development of 2,5-disubstituted-1,3,4-oxadiazole analogues as active LOX, urease, and α-glucosidase inhibitors. [PDF]

Sci Rep
Javid J, Aziz-Ur-Rehman, Iqbal J, Ahmed I, Bhatti N, Kuznetsov A, Zafar F, Ayub MA, Mohammed OA, Al-Mijalli SH, Iqbal M, Shah SAA.   +11 more
europepmc   +1 more source

Biomodification of dentin collagen with hydroalcoholic propolis extract: Impact on resin–dentin adhesion

European Journal of Oral Sciences, Volume 134, Issue 2, April 2026.
Abstract This in vitro study evaluated the effect of hydroalcoholic propolis extract (HPE) as a collagen cross‐linking agent for preserving the dentin–adhesive interface. Dentin beams from human third molars were demineralized with 10% phosphoric acid and assigned to five treatments: distilled water (control), 6.5% grape seed extract (GSE), and HPE at ...
Zidane Hurtado Rabelo, Edinaldo Gomes de Meneses Neto, Israel Simon Andrade Costa, Juliano Sartori Mendonça, Vanara Florêncio Passos, Sérgio Lima Santiago   +5 more
wiley   +1 more source

Bioactive Flavonoids from <i>Paulownia tomentosa</i> Flowers: Extraction Optimization and α-Glucosidase Inhibitory Kinetics. [PDF]

Foods
Jiang F, Yang H, Zhai X, Zhao Z, Fan G.
europepmc   +1 more source

First Detection of Lactococcus formosensis subsp. formosensis in Rainbow Trout (Oncorhynchus mykiss) in Europe

Journal of Fish Diseases, Volume 49, Issue 4, April 2026.
ABSTRACT Lactococcus garvieae, Lactococcus petauri and Lactococcus formosensis are etiological agents of piscine lactococcosis, a disease reported in Italy since the early 1990s and linked to significant aquaculture losses. To the best of our knowledge, this study reports the first detection of L. formosensis subsp. formosensis in farmed rainbow trout (
Silvia Colussi, Giuseppe Esposito, Khalid Shahin, Pier Luigi Acutis, Lucio Fariano, Claudio Ghittino, Maria Goria, Fabio Bondavalli, Paolo Ajmone Marsan, Giorgia Bignami, Elena Bozzetta, Marino Prearo, Paolo Pastorino   +12 more
wiley   +1 more source

Design, synthesis, <i>in vitro</i>, and <i>in silico</i> studies on promising α-glucosidase inhibitors based on a quinazolinone-thiophene scaffold. [PDF]

RSC Adv
Baghershahi P, Dastyafteh N, Halimi M, Mohammadi-Khanaposhtani M, Ghafouri SN, Noori M, Ghasemi F, Mojtabavi S, Faramarzi MA, Torabi M, Alikhani M, Larijani B, Javanshir S, Mahdavi M.   +13 more
europepmc   +1 more source

Comparative effects of superheated steam and hot air roasting on the in vitro phospholipase A2 inhibitory activity and polyphenol composition of cocoa beans

Journal of the Science of Food and Agriculture, Volume 106, Issue 5, Page 3200-3207, 30 March 2026.
Abstract Background Cocoa, derived from Theobroma cacao, is a popular food ingredient used to produce chocolate. Cocoa is rich in polyphenols and human and laboratory model studies have indicated that cocoa and chocolate can mitigate chronic inflammatory conditions.
Sawali Navare, Bethany H. Lam, Misha T. Kwasniewski, Ramaswamy Anantheswaran, Joshua D. Lambert   +4 more
wiley   +1 more source

Functional Analysis of Amino Acid Residues Responsible for Substrate Specificity of GH13_17 α‑Glucosidase from <i>Aedes aegypti</i> Saliva (AaMalI). [PDF]

ACS Omega
Auiewiriyanukul W, Saburi W, Mori H, Arthan D, Tharamak S.   +4 more
europepmc   +1 more source

Quinic Acid and Synthetic Derivatives in Medicinal Chemistry

ChemMedChem, Volume 21, Issue 5, 13 March 2026.
Quinic acid and its derivatives are gaining recognition as versatile scaffolds in drug discovery. This review explores their emerging roles in inflammation, infection, cancer, and metabolic disorders, highlighting recent advances that position them beyond chlorogenic acids as promising platforms for therapeutic innovation. Quinic acid (QA) is a natural
Iago C. Vogel, Manuel J. Verganista, Nuno R. Candeias   +2 more
wiley   +1 more source

Rational design and synthesis of new acetamide-indole-benzo[d]imidazole-carboxylic acid hybrids as dual PTP1B/α-glucosidase inhibitors. [PDF]

RSC Adv
Dastyafteh N, Ghafouri SN, Mollazadeh M, Motamedi Shakib N, Halimi M, Hosseini S, Mojtabavi S, Faramarzi MA, Larijani B, Amanlou M, Mohammadi-Khanaposhtani M, Mahdavi M.   +11 more
europepmc   +1 more source