Results 161 to 170 of about 975,489 (310)

α-Glucosidase inhibitory activity of polyphenol-rich sugarcane extract: screening and mechanistic insights based on biolayer interferometry-mass spectrometry

open access: yesFrontiers in Nutrition
IntroductionPolyphenol-rich sugarcane extract (PRSE) contains bioactive compounds with potential hypoglycemic properties, but its direct interaction with α-glucosidase has not been explored.MethodsThis study investigated the inhibitory mechanism of PRSE ...
Mengli Yao   +12 more
doaj   +1 more source

Optimized Fertilization Balances Microbial Carbon and Nitrogen Use Efficiency: Evidence From Microbial Communities

open access: yesLand Degradation &Development, EarlyView.
ABSTRACT Optimized fertilization involving reduced mineral N input and organic substitution can alter resource stoichiometry, microbial carbon use efficiency (CUE) and nitrogen use efficiency (NUE). However, how fertilization‐induced resource imbalance reshapes microbial community to regulate CUE and NUE remains unclear. We conducted a field experiment
Yazhen Chen   +11 more
wiley   +1 more source

Bioactive Natural Products in Cardiovascular Disease: Focus on Thrombotic Events

open access: yesPhytotherapy Research, EarlyView.
An overview of the role of natural products (NP) in cardiovascular disease prevention, highlighting key mechanisms of action: including antiplatelet, antithrombotic, anti‐inflammatory, and antioxidant effects. Additionally, it illustrates the integration of diet–drug interactions, nutritional epigenetics, and the role of artificial intelligence in ...
Maria Nektaria Magkoulia   +1 more
wiley   +1 more source

α-Glucosidase Inhibitors from Vauquelinia corymbosa

open access: yes, 2015
The α-glucosidase inhibitory activity of an aqueous extract and compounds from the aerial parts of V. corymbosa was demonstrated with yeast and rat small intestinal α-glucosidases.
Robert Bye   +5 more
core   +1 more source

Dipeptidyl Peptidase‐4 Inhibitor Use and Risk of Pemphigus Vulgaris and Foliaceus: A Retrospective Cohort Study Using Databases of the Korea National Health Insurance Claims and the National Health Screening Examination

open access: yesThe Journal of Dermatology, EarlyView.
ABSTRACT Although population‐based studies have reported an increased risk of bullous pemphigoid and pemphigus associated with dipeptidyl peptidase‐4 (DPP‐4) inhibitors, there is limited, well‐designed epidemiological evidence for pemphigus vulgaris (PV), which has only been supported by case reports thus far.
Jaein Lee, Jae Hyun Bae, Seokyung Hahn
wiley   +1 more source

Goose herbivory alters soil microbial community functional potential in a sub‐Arctic wetland

open access: yesFunctional Ecology, EarlyView.
Read the free Plain Language Summary for this article on the Journal blog. Abstract Herbivory alters below‐ground resource dynamics via direct and indirect mechanisms, yet its effects on microbial functional potential remain poorly understood. This limits our understanding of the mechanisms that link animal, plant and microbial functional roles in ...
Jaron Adkins   +8 more
wiley   +1 more source

Distribution of β-glucosidase and β-glucuronidase activity and of β-glucuronidase gene gus in human colonic bacteria [PDF]

open access: yesFEMS Microbiology Ecology, 2008
Marta Dabek   +4 more
openaire   +1 more source

Maltase 1 regulates DENV2 infection and life history in Aedes aegypti

open access: yesInsect Science, EarlyView.
Our study employed CRISPR/Cas9 to generate a MAL1 knockout strain of Aedes aegypti, demonstrating that the absence of MAL1 significantly suppresses DENV2 replication in the midgut and impairs viral transmission. The mutation also altered life‐history (hatching/pupation/emerging rates and sex‐specific survival), identifying MAL1 as a novel target for ...
Man‐Jin Li   +5 more
wiley   +1 more source

TcALS knockdown accelerates metamorphosis via insulin signaling in Tribolium castaneum

open access: yesInsect Science, EarlyView.
RNAi silencing of TcALS accelerates larva‐to‐pupa metamorphosis in Tribolium castaneum. Abstract Insect metamorphosis is an evolutionary adaptation precisely regulated by nutritional and hormonal cues. The red flour beetle Tribolium castaneum, a major stored‐product pest, serves as an excellent model for studying this process.
Min Li   +8 more
wiley   +1 more source

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